Protein Alignment KrT95D and Pacs1

DIOPT Version :10

• Sequence 1: NP_524473.2
• Gene: KrT95D / 42843
• FlyBaseID: FBgn0020647
• Length: 1175
• Species: Drosophila melanogaster
• Sequence 2: NP_599233.1
• Gene: Pacs1 / 171444
• RGDID: 620579
• Length: 961
• Species: Rattus norvegicus
• Alignment Length: 1223
• Identity: 376/1223 - (30%)
• Similarity: 529/1223 - (43%)
• Gaps: 346/1223 - (28%)

  Fly    24 GPGGGPLNLQSGGGGGGSGGGGGV---------------------------SGSGGISGTAGLSA 61
            |.||||    .|.|||.|..|.||                           |.|...|..|..|:
  Rat     6 GAGGGP----GGAGGGSSQRGSGVAQSPQQQPPQQPSQPQQPTPPKLAQATSSSSSTSAAAASSS 66

  Fly    62 GAGMTT------------------GQKPVP--MKLFAAWEVDRTPPNCIPRLCSLTITRLSILTP 106
            .:..:|                  |:.|.|  |.|:|.|||||:..:|:|||.|||:.:|.:|..
  Rat    67 SSSTSTSMAVAVASGSAPPGGPGPGRTPAPVQMNLYATWEVDRSSSSCVPRLFSLTLKKLVMLKE 131

  Fly   107 LPGDTTSLSLAVKMQSSKRTLRSHEI--PINGLALTSSASLQGNSPMSVAGGVGGGGVGTPGSVG 169
            :..|..|:.:|||:|.|||.|||:||  |.:|
  Rat   132 MDKDLNSVVIAVKLQGSKRILRSNEIILPASG--------------------------------- 163

  Fly   170 TGGGLGVAVPLTETELDLHFSLQYPHFIKRDGNRLVILLQRRKKYKSRTILGYKTLAEGIIRMDA 234
                      |.||||.|.||||||||:|||.|:|.|:|||||:||:||||||||||.|:|.|..
  Rat   164 ----------LVETELQLTFSLQYPHFLKRDANKLQIMLQRRKRYKNRTILGYKTLAVGLINMAE 218

  Fly   235 VLQKSMD--MIIELTASGKNGRPGTVVACLRAERVSSIPVDHDNKNNNSVLLADR---VAEYSDE 294
            |:|...:  :::.|.::.|:  ....||.::...:||.|:||:...:.   |:||   :..||:|
  Rat   219 VMQHPNEGALVLGLHSNVKD--VSVPVAEIKIYSLSSQPIDHEGIKSK---LSDRSPDIDNYSEE 278

  Fly   295 DEEAEFSSGEFNDEANELGLIRGYDPKDPRDYNHPAKHDMRKYRNKLQRSGIEDCALVGHHPGSI 359
            :||:..|..|.:|           ||...:|..: ...|:||.:
  Rat   279 EEESFSSEQEGSD-----------DPLHGQDLFY-EDEDLRKVK--------------------- 310

  Fly   360 QHHHPGVVVDSDSEFEMKDKSSSRAKFSRTISL-QQRNFKQKIVALLKRFKVSEELEGESGHRGT 423
                                 .:|.|.:.|.:: :|.|.|||.||||||||||:|:.....|...
  Rat   311 ---------------------KTRRKLTSTSAITRQPNIKQKFVALLKRFKVSDEVGFGLEHVSR 354

  Fly   424 AALRG-ERDLDALFQELESLSCCEGDDSGPDMDSI-SVGSTPKPSLRPFFTNSRIMLHDNITGNG 486
            ..:|. |.|||.|:..||..:   ..||||:|:.. |:.|||||.|:|||           .|..
  Rat   355 EQIREVEEDLDELYDSLEMYN---PSDSGPEMEETESILSTPKPKLKPFF-----------EGMS 405

  Fly   487 GDLSQLVGGGLGPGTGTAGNSERRSSDKSDQLTNSSYNLENNKNQKCIHLTNNNNSATTPDRGGN 551
            ...||...|.|. ..|:.|..           |.|...|...:..|...:.|.::|.|..|
  Rat   406 QSSSQTEIGSLN-SKGSLGKD-----------TTSPMELAALEKVKSTWIKNQDDSLTETD---- 454

  Fly   552 DSSGNEGNAGYTD----GQNSDPQNSPPRDKDYLRLQQMQQQQLTPVSSVAASM-GSGSVITPAQ 611
                   ....||    |..|.....|.:.|             ||:.|..|.: ||.|   |::
  Rat   455 -------TLEITDQDMFGDASTSLVVPEKVK-------------TPMKSSKADLQGSAS---PSK 496

  Fly   612 TEKRSRLFRTSSNTPANAGSGGNSVSAISASGGGKRKHTLSLSAEPRSVLEACLSPTNVEPRKLL 676
            .| .:...|...:||.........:|..:.|...:|...|..|.:              .|||::
  Rat   497 VE-GTHTPRQKRSTPLKERQLSKPLSERTNSSDSERSPDLGHSTQ--------------IPRKVV 546

  Fly   677 LDQLSRVFAGEDSAIPEVVTIISPPEALGGSALLAKLVTLFANSFKPAFVPQNTAEVKAVLQALM 741
            .|||:::.. .|:|:||.|.:::..:..|     ..:..|..:..||.....:|.||:|||.||:
  Rat   547 YDQLNQILV-SDAALPENVILVNTTDWQG-----QYVAELLQDQRKPVVCTCSTVEVQAVLSALL 605

  Fly   742 AKIQKYCNSNAKPPHTVKVLLIGGDWLQGATLRHYVELMGVRPPDWLNHLRFYLVPVGGSCGSVA 806
            .:||:|||.|:..|..|||..:|......:.||.:|:.:..:.||||.|:||.:||:|..  .||
  Rat   606 TRIQRYCNCNSSMPRPVKVAAVGSQSYLSSILRFFVKSLASKTPDWLGHMRFLIVPLGSH--PVA 668

  Fly   807 RHLSQMDQAYAVMFGSDNWTQLCERAAATAAAVSAVTTVNATALTTNLADAAGVAKSDIAELVQR 871
            ::|..:|..|:..|....|..|..|:....                          |:..::|.|
  Rat   669 KYLGSVDSRYSSTFLDSAWRDLFSRSEPPV--------------------------SEPLDVVGR 707

  Fly   872 IQRYLLAAGPCTQIPIAEAMV----NYKDEDSCQIFVPFVSDVRIGYLDAQASLDLEENAAGSNA 932
            :.:|:..|....|:|:||||:    .:.||||.|.|:||:..|::|.::...|.
  Rat   708 VMQYVNGATTTHQLPVAEAMLTCRHKFPDEDSYQKFIPFIGVVKVGLVEDSPST----------- 761

  Fly   933 VGSGLGSGSASSSAIPIGSQSSPNVHGVVSGSPPQQQSLGRISPPLQTPPSSASSHRERNTSESL 997
                .|.|..|    |:.|.:.|      |.|||....|.|  ....|||||
  Rat   762 ----AGDGDDS----PVVSLTVP------STSPPSSSGLSR--DATATPPSS------------- 797

  Fly   998 STPSSVQQQSFSGALAA--------AEAVELQVDYWPLVRPGEGHAKESKGGLSKGSDAGGKNSI 1054
                    .|.|.|||.        .:.:.|||||| |..|||...:..|      .||..||::
  Rat   798 --------PSMSSALAIVGSPNSPYGDVIGLQVDYW-LGHPGERRREGDK------RDASSKNTL 847

  Fly  1055 KSTFRNLQVWRLPQ--HAQQLGDMFNGLTVSFATKEKKQKQIMRLGKKKDKERDLE-KEQCVEGV 1116
            ||.||::||.|||.  .||..|.|  .:||  .||||.:|.......||.:|:::: |.|.:||:
  Rat   848 KSVFRSVQVSRLPHAGEAQLSGTM--AMTV--VTKEKNKKVPTIFLSKKPREKEVDSKSQVIEGI 908

  Fly  1117 ARLICSPKQSHPVPLRVYIDGTEWTGVKFFQVSSQWQTHVKNFPIALI-GCTP 1168
            :|||||.||...: |||.|||.||:.:||||:::||.||||:||:.|. |..|
  Rat   909 SRLICSAKQQQTM-LRVSIDGVEWSDIKFFQLAAQWPTHVKHFPVGLFSGSKP 960

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
KrT95D	NP_524473.2	Pacs-1	676..1167	CDD:463027	168/506 (33%)
Pacs1	NP_599233.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..70		18/67 (27%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	76..95		1/18 (6%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	260..297		13/50 (26%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	375..426		22/76 (29%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	475..540		18/81 (22%)
		Pacs-1	546..958	CDD:463027	167/505 (33%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	758..802		19/91 (21%)