Protein Alignment KrT95D and Pacs1

DIOPT Version :10

• Sequence 1: NP_524473.2
• Gene: KrT95D / 42843
• FlyBaseID: FBgn0020647
• Length: 1175
• Species: Drosophila melanogaster
• Sequence 2: NP_001390496.1
• Gene: Pacs1 / 107975
• MGIID: 1277113
• Length: 987
• Species: Mus musculus
• Alignment Length: 1238
• Identity: 371/1238 - (29%)
• Similarity: 530/1238 - (42%)
• Gaps: 361/1238 - (29%)

  Fly    24 GPGGGPLNLQSGGGGGGSGGGGGV---------------------------SGSGGISGTAGLSA 61
            |.||||    .|.|||.|..|.||                           |.|...|..|..|:
Mouse     6 GAGGGP----GGSGGGSSQRGSGVAQSPQQQPQQQPPQPQQPTPPKLAQATSSSSSTSAAAASSS 66

  Fly    62 GAGMTT------------------GQKPVP--MKLFAAWEVDRTPPNCIPRLCSLTITRLSILTP 106
            .:..:|                  |:.|.|  |.|:|.|||||:..:|:|||.|||:.:|.:|..
Mouse    67 SSSTSTSMAVAVASGSAPPGGPGPGRTPAPVQMNLYATWEVDRSSSSCVPRLFSLTLKKLVMLKE 131

  Fly   107 LPGDTTSLSLAVKMQSSKRTLRSHEI--PINGLALTSSASLQGNSPMSVAGGVGGGGVGTPGSVG 169
            :..|..|:.:|||:|.|||.|||:||  |.:|
Mouse   132 MDKDLNSVVIAVKLQGSKRILRSNEIILPASG--------------------------------- 163

  Fly   170 TGGGLGVAVPLTETELDLHFSLQYPHFIKRDGNRLVILLQRRKKYKSRTILGYKTLAEGIIRMD- 233
                      |.||||.|.||||||||:|||.|:|.|:|||||:||:||||||||||.|:|.|.
Mouse   164 ----------LVETELQLTFSLQYPHFLKRDANKLQIMLQRRKRYKNRTILGYKTLAVGLINMAE 218

  Fly   234 --------------------AVLQKSMD--MIIELTASGKNGRPGTVVACLRAERVSSIPVDHDN 276
                                .|:|...:  :::.|.::.|:  ....||.::...:||.|:||:.
Mouse   219 YSYVSKTKKKEAARQLFKLFLVMQHPNEGALVLGLHSNVKD--VSVPVAEIKIYSLSSQPIDHEG 281

  Fly   277 KNNNSVLLADR---VAEYSDEDEEAEFSSGEFNDEANELGLIRGYDPKDPRDYNHPAKHDMRKYR 338
            ..:.   |:||   :..||:|:||:..|..|.:|           ||...:|..: ...|:||.:
Mouse   282 IKSK---LSDRSPDIDNYSEEEEESFSSEQEGSD-----------DPLHGQDLFY-EDEDLRKVK 331

  Fly   339 NKLQRSGIEDCALVGHHPGSIQHHHPGVVVDSDSEFEMKDKSSSRAKFSRTISL-QQRNFKQKIV 402
                                                      .:|.|.:.|.:: :|.|.|||.|
Mouse   332 ------------------------------------------KTRRKLTSTSAITRQPNIKQKFV 354

  Fly   403 ALLKRFKVSEELEGESGHRGTAALRG-ERDLDALFQELESLSCCEGDDSGPDMDSI-SVGSTPKP 465
            |||||||||:|:.....|.....:|. |.|||.|:..||..:   ..||||:|:.. |:.|||||
Mouse   355 ALLKRFKVSDEVGFGLEHVSREQIREVEEDLDELYDSLEMYN---PSDSGPEMEETESILSTPKP 416

  Fly   466 SLRPFFTNSRIMLHDNITGNGGDLSQLVGGGLGPGTGTAGNSERRSSDKSDQLTNSSYNLENNKN 530
            .|:|||           .|.....||...|.|. ..|:.|      .|.:..::.:...|...:.
Mouse   417 KLKPFF-----------EGMSQSSSQTEIGSLN-SKGSLG------KDTTSPVSRTMMELAALEK 463

  Fly   531 QKCIHLTNNNNSATTPDRGGNDSSGNEGNAGYTD----GQNSDPQNSPPRDKDYLRLQQMQQQQL 591
            .|...:.|.::|.|..|           ....||    |..|.....|.:.|
Mouse   464 VKSTWIKNQDDSLTETD-----------TLEITDQDMFGDVSTSLVVPEKVK------------- 504

  Fly   592 TPVSSVAASM-GSGSVITPAQTEKRSRLFRTSSNTPANAGSGGNSVSAISASGGGKRKHTLSLSA 655
            ||:.|..|.: ||.|   |::.| .:...|...:||.........:|..:.|...:|...|..|.
Mouse   505 TPMKSSKADLQGSAS---PSKVE-GTHTPRQKRSTPLKERQLSKPLSERTNSSDSERSPDLGHST 565

  Fly   656 EPRSVLEACLSPTNVEPRKLLLDQLSRVFAGEDSAIPEVVTIISPPEALGGSALLAKLVTLFANS 720
            :              .|||::.|||:::.. .|:|:||.|.:::..:..|     ..:..|..:.
Mouse   566 Q--------------IPRKVVYDQLNQILV-SDAALPENVILVNTTDWQG-----QYVAELLQDQ 610

  Fly   721 FKPAFVPQNTAEVKAVLQALMAKIQKYCNSNAKPPHTVKVLLIGGDWLQGATLRHYVELMGVRPP 785
            .||.....:|.||:|||.||:.:||:|||.|:..|..|||..:|......:.||.:|:.:..:.|
Mouse   611 RKPVVCTCSTVEVQAVLSALLTRIQRYCNCNSSMPRPVKVAAVGSQSYLSSILRFFVKSLASKTP 675

  Fly   786 DWLNHLRFYLVPVGGSCGSVARHLSQMDQAYAVMFGSDNWTQLCERAAATAAAVSAVTTVNATAL 850
            |||.::||.::|:|..  .||::|..:|..|:..|....|..|..|:....
Mouse   676 DWLGYMRFLIIPLGSH--PVAKYLGSVDSRYSSTFLDSAWRDLFSRSEPPV-------------- 724

  Fly   851 TTNLADAAGVAKSDIAELVQRIQRYLLAAGPCTQIPIAEAMV----NYKDEDSCQIFVPFVSDVR 911
                        |:..::|.|:.:|:..|....|:|:||||:    .:.||||.|.|:||:..|:
Mouse   725 ------------SEPLDVVGRVMQYVNGATTTHQLPVAEAMLTCRHKFPDEDSYQKFIPFIGVVK 777

  Fly   912 IGYLDAQASLDLEENAAGSNAVGSGLGSGSASSSAIPIGSQSSPNVHGVVSGSPPQQQSLGRISP 976
            :|.::...|.               .|.|..|    |:.|.:.|      |.|||....|.|  .
Mouse   778 VGLVEDSPST---------------AGDGDDS----PVVSLTVP------STSPPSSSGLSR--D 815

  Fly   977 PLQTPPSSASSHRERNTSESLSTPSSVQQQSFSGALAA--------AEAVELQVDYWPLVRPGEG 1033
            ...|||||                     .|.|.|||.        .:.:.|||||| |..|||.
Mouse   816 ATATPPSS---------------------PSMSSALAIVGSPNSPYGDVIGLQVDYW-LGHPGER 858

  Fly  1034 HAKESKGGLSKGSDAGGKNSIKSTFRNLQVWRLPQ--HAQQLGDMFNGLTVSFATKEKKQKQIMR 1096
            ..:..|      .||..||::||.||::||.|||.  .||..|.|  .:||  .||||.:|....
Mouse   859 RREGDK------RDASSKNTLKSVFRSVQVSRLPHAGEAQLSGTM--AMTV--VTKEKNKKVPTI 913

  Fly  1097 LGKKKDKERDLE-KEQCVEGVARLICSPKQSHPVPLRVYIDGTEWTGVKFFQVSSQWQTHVKNFP 1160
            ...||.:|:::: |.|.:||::|||||.||...: |||.|||.||:.:||||:::||.||||:||
Mouse   914 FLSKKPREKEVDSKSQVIEGISRLICSAKQQQTM-LRVSIDGVEWSDIKFFQLAAQWPTHVKHFP 977

  Fly  1161 IAL 1163
            :.|
Mouse   978 VGL 980

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
KrT95D	NP_524473.2	Pacs-1	676..1167	CDD:463027	165/503 (33%)
Pacs1	NP_001390496.1	Pacs-1	572..984	CDD:463027	165/503 (33%)