DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rab7 and GSP2

DIOPT Version :9

Sequence 1:	NP_001247276.1	Gene:	Rab7 / 42841	FlyBaseID:	FBgn0015795	Length:	207	Species:	Drosophila melanogaster
Sequence 2:	NP_014828.1	Gene:	GSP2 / 854357	SGDID:	S000005711	Length:	220	Species:	Saccharomyces cerevisiae

Alignment Length:	201	Identity:	57/201 - (28%)
Similarity:	102/201 - (50%)	Gaps:	26/201 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 KVIILGDSSVGKTSLMNQYVNKRFSNQYKATIGADFCTKEVVVNDRVVTMQIWDTAGQERFQSLG 74
            |::::||...|||:.:.:::...|..:|.||||.:........|...:...:|||||||:|..|.
Yeast    15 KLVLVGDGGTGKTTFVKRHLTGEFEKKYIATIGVEVHPLSFYTNFGEIKFDVWDTAGQEKFGGLR 79

  Fly    75 VAFYRGADCCVLVYDVTAPNSFKNLDSWRDEFLIQASPRDPDHFPFVVLGNKVDLDNRQVSTRRA 139
            ..:|..|.|.::::|||:..::||:.:|..:.:     |..::.|.|:.|||||:..|:|..:..
Yeast    80 DGYYINAQCAIIMFDVTSRITYKNVPNWHRDLV-----RVCENIPIVLCGNKVDVKERKVKAKTI 139

  Fly   140 QQWCQSKNDIPYYETSAKEGINVEMAF-------------QVIAKNAL---ELEAEAEVINDFP- 187
            .  ...|.::.||:.|||...|.|..|             :.:|..||   |::.:.::::.:.
Yeast   140 T--FHRKKNLQYYDISAKSNYNFEKPFLWLARKLAGNPQLEFVASPALAPPEVQVDEQLMHQYQQ 202

  Fly   188 --DQIT 191
              ||.|
Yeast   203 EMDQAT 208

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rab7	NP_001247276.1	Rab7	9..179	CDD:206655	54/184 (29%)
Rab7	NP_001247276.1	RAB	9..174	CDD:197555	51/176 (29%)
GSP2	NP_014828.1	PTZ00132	5..217	CDD:240284	57/201 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910