DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rab7 and GSP1

DIOPT Version :9

Sequence 1:	NP_001247276.1	Gene:	Rab7 / 42841	FlyBaseID:	FBgn0015795	Length:	207	Species:	Drosophila melanogaster
Sequence 2:	NP_013396.1	Gene:	GSP1 / 851000	SGDID:	S000004284	Length:	219	Species:	Saccharomyces cerevisiae

Alignment Length:	210	Identity:	56/210 - (26%)
Similarity:	103/210 - (49%)	Gaps:	23/210 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 KVIILGDSSVGKTSLMNQYVNKRFSNQYKATIGADFCTKEVVVNDRVVTMQIWDTAGQERFQSLG 74
            |::::||...|||:.:.:::...|..:|.||||.:........|...:...:|||||||:|..|.
Yeast    14 KLVLVGDGGTGKTTFVKRHLTGEFEKKYIATIGVEVHPLSFYTNFGEIKFDVWDTAGQEKFGGLR 78

  Fly    75 VAFYRGADCCVLVYDVTAPNSFKNLDSWRDEFLIQASPRDPDHFPFVVLGNKVDLDNRQVSTRRA 139
            ..:|..|.|.::::|||:..::||:.:|..:.:     |..::.|.|:.|||||:..|:|..:..
Yeast    79 DGYYINAQCAIIMFDVTSRITYKNVPNWHRDLV-----RVCENIPIVLCGNKVDVKERKVKAKTI 138

  Fly   140 QQWCQSKNDIPYYETSAKEGINVEMAF-------------QVIAKNAL---ELEAEAEVINDFPD 188
            .  ...|.::.||:.|||...|.|..|             :.:|..||   |::.:.:::..:..
Yeast   139 T--FHRKKNLQYYDISAKSNYNFEKPFLWLARKLAGNPQLEFVASPALAPPEVQVDEQLMQQYQQ 201

  Fly   189 QITLGSQNNRPGNPD 203
            ::...:....|...|
Yeast   202 EMEQATALPLPDEDD 216

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rab7	NP_001247276.1	Rab7	9..179	CDD:206655	54/184 (29%)
Rab7	NP_001247276.1	RAB	9..174	CDD:197555	51/176 (29%)
GSP1	NP_013396.1	PTZ00132	4..216	CDD:240284	55/208 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910