Protein Alignment Rab7 and RAB7A

DIOPT Version :9

• Sequence 1: NP_001247276.1
• Gene: Rab7 / 42841
• FlyBaseID: FBgn0015795
• Length: 207
• Species: Drosophila melanogaster
• Sequence 2: NP_004628.4
• Gene: RAB7A / 7879
• HGNCID: 9788
• Length: 207
• Species: Homo sapiens
• Alignment Length: 207
• Identity: 158/207 - (76%)
• Similarity: 182/207 - (87%)
• Gaps: 0/207 - (0%)

  Fly     1 MSGRKKSLLKVIILGDSSVGKTSLMNQYVNKRFSNQYKATIGADFCTKEVVVNDRVVTMQIWDTA 65
            |:.|||.||||||||||.|||||||||||||:|||||||||||||.||||:|:||:|||||||||
Human     1 MTSRKKVLLKVIILGDSGVGKTSLMNQYVNKKFSNQYKATIGADFLTKEVMVDDRLVTMQIWDTA 65

  Fly    66 GQERFQSLGVAFYRGADCCVLVYDVTAPNSFKNLDSWRDEFLIQASPRDPDHFPFVVLGNKVDLD 130
            ||||||||||||||||||||||:||||||:||.|||||||||||||||||::|||||||||:||:
Human    66 GQERFQSLGVAFYRGADCCVLVFDVTAPNTFKTLDSWRDEFLIQASPRDPENFPFVVLGNKIDLE 130

  Fly   131 NRQVSTRRAQQWCQSKNDIPYYETSAKEGINVEMAFQVIAKNALELEAEAEVINDFPDQITLGSQ 195
            ||||:|:|||.||.|||:|||:||||||.||||.|||.||:|||:.|.|.|:.|:||:.|.|...
Human   131 NRQVATKRAQAWCYSKNNIPYFETSAKEAINVEQAFQTIARNALKQETEVELYNEFPEPIKLDKN 195

  Fly   196 NNRPGNPDNCQC 207
            :....:.::|.|
Human   196 DRAKASAESCSC 207

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rab7	NP_001247276.1	Rab7	9..179	CDD:206655	144/169 (85%)
		RAB	9..174	CDD:197555	141/164 (86%)
RAB7A	NP_004628.4	Rab7	9..179	CDD:206655	144/169 (85%)
		Effector region. /evidence=ECO:0000250	37..45		7/7 (100%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165157030
Domainoid	1	1.000	299	1.000	Domainoid score	I1439
eggNOG	1	0.900	-	-		E1_KOG0394
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	334	1.000	Inparanoid score	I2420
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1172019at2759
OrthoFinder	1	1.000	-	-		FOG0001661
OrthoInspector	1	1.000	-	-		oto89779
orthoMCL	1	0.900	-	-		OOG6_101358
Panther	1	1.100	-	-	LDO	PTHR47981
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2001
SonicParanoid	1	1.000	-	-		X1058
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	14	13.790