DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rab7 and Rab3b

DIOPT Version :9

Sequence 1:	NP_001247276.1	Gene:	Rab7 / 42841	FlyBaseID:	FBgn0015795	Length:	207	Species:	Drosophila melanogaster
Sequence 2:	NP_076026.1	Gene:	Rab3b / 69908	MGIID:	1917158	Length:	219	Species:	Mus musculus

Alignment Length:	208	Identity:	68/208 - (32%)
Similarity:	113/208 - (54%)	Gaps:	18/208 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 LLKVIILGDSSVGKTSLMNQYVNKRFSNQYKATIGADFCTKEVVVNDRVVTMQIWDTAGQERFQS 72
            :.|::|:|:|||||||.:.:|.:..|:..:.:|:|.||..|.|..:::.|.:||||||||||:::
Mouse    22 MFKLLIIGNSSVGKTSFLFRYADDTFTPAFVSTVGIDFKVKTVYRHEKRVKLQIWDTAGQERYRT 86

  Fly    73 LGVAFYRGADCCVLVYDVTAPNSFKNLDSWRDEFLIQASPRDPDHFPFVVLGNKVDLDNRQVSTR 137
            :..|:||||...:|:||:|...||..:..|    ..|......|:...:::|||.|::..:|...
Mouse    87 ITTAYYRGAMGFILMYDITNEESFNAVQDW----ATQIKTYSWDNAQVILVGNKCDMEEERVVPT 147

  Fly   138 RAQQWCQSKNDIPYYETSAKEGINVEMAFQVIAKNALELEAEAEVINDF--PDQITLG-SQNNR- 198
            ...:....:....::|.||||.|:|..||:.:      ::|..:.::|.  .|...|| |:..|
Mouse   148 EKGRLLAEQLGFDFFEASAKENISVRQAFERL------VDAICDKMSDSMDTDPSVLGASKTTRL 206

  Fly   199 ----PGNPDNCQC 207
                |....||.|
Mouse   207 SDTPPLLQQNCSC 219

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rab7	NP_001247276.1	Rab7	9..179	CDD:206655	57/169 (34%)
Rab7	NP_001247276.1	RAB	9..174	CDD:197555	57/164 (35%)
Rab3b	NP_076026.1	Rab3	22..186	CDD:206657	58/173 (34%)
Rab3b	NP_076026.1	Effector region. /evidence=ECO:0000250	51..59		2/7 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910