DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rab7 and Rab13

DIOPT Version :9

Sequence 1:	NP_001247276.1	Gene:	Rab7 / 42841	FlyBaseID:	FBgn0015795	Length:	207	Species:	Drosophila melanogaster
Sequence 2:	NP_080953.1	Gene:	Rab13 / 68328	MGIID:	1927232	Length:	202	Species:	Mus musculus

Alignment Length:	168	Identity:	65/168 - (38%)
Similarity:	107/168 - (63%)	Gaps:	6/168 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 LLKVIILGDSSVGKTSLMNQYVNKRFSNQYKATIGADFCTKEVVVNDRVVTMQIWDTAGQERFQS 72
            |.|::::|||.||||.|:.::....|::.|.:|||.||..:.|.:..:.:.:|:|||||||||::
Mouse     8 LFKLLLIGDSGVGKTCLIIRFAEDNFNSTYISTIGIDFKIRTVDIEGKRIKLQVWDTAGQERFKT 72

  Fly    73 LGVAFYRGADCCVLVYDVTAPNSFKNLDSWRDEFLIQASPRDPDHFPFVVLGNKVDLD-NRQVST 136
            :..|:||||...:||||:|...||:|:.:|.......||.    ....::||||.|:: .|||..
Mouse    73 ITTAYYRGAMGIILVYDITDEKSFENIQNWMKSIKENASA----GVERLLLGNKCDMEAKRQVQR 133

  Fly   137 RRAQQWCQSKNDIPYYETSAKEGINVEMAFQVIAKNAL 174
            .:|::..: ::.|.::|||||..:||:.||..:|::.|
Mouse   134 EQAEKLAR-EHRIRFFETSAKSSVNVDEAFSSLARDIL 170

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rab7	NP_001247276.1	Rab7	9..179	CDD:206655	64/167 (38%)
Rab7	NP_001247276.1	RAB	9..174	CDD:197555	63/165 (38%)
Rab13	NP_080953.1	Rab8_Rab10_Rab13_like	6..172	CDD:206659	65/168 (39%)
		RAB	9..170	CDD:197555	63/165 (38%)
		Effector region. /evidence=ECO:0000250	37..45		4/7 (57%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	174..202
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910