DRSC/TRiP Functional Genomics Resources

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Protein Alignment Rab7 and Rab32

DIOPT Version :9

Sequence 1:NP_001247276.1 Gene:Rab7 / 42841 FlyBaseID:FBgn0015795 Length:207 Species:Drosophila melanogaster
Sequence 2:NP_080681.1 Gene:Rab32 / 67844 MGIID:1915094 Length:223 Species:Mus musculus


Alignment Length:217 Identity:71/217 - (32%)
Similarity:117/217 - (53%) Gaps:28/217 - (12%)


- Green bases have known domain annotations that are detailed below.


  Fly     5 KKSLLKVIILGDSSVGKTSLMNQYVNKRFSNQYKATIGADFCTKEVVVNDR-VVTMQIWDTAGQE 68
            ::.|.||:::|:..|||||::.:||::.||..|:||||.||..|.:..:.| :|.:|:||.||||
Mouse    20 REHLFKVLVIGELGVGKTSIIKRYVHQLFSQHYRATIGVDFALKVLNWDSRTLVRLQLWDIAGQE 84

  Fly    69 RFQSLGVAFYRGADCCVLVYDVTAPNSFKNLDSWRDEF-----LIQASPRDPDHFPFVVLGNKVD 128
            ||.::...:|:.|....:|:|::..::|..:..|:::.     |...||     .|.|:|.||.|
Mouse    85 RFGNMTRVYYKEALGAFVVFDISRSSTFDAVLKWKNDLDSKVHLPNGSP-----IPAVLLANKCD 144

  Fly   129 --LDNRQVSTRRAQQWCQSKNDIPYYETSAKEGINVEMAFQVIAKNALELEAEAEVINDFP---- 187
              .||.| |..:..|:|:......::|||||:.||::.|.:.:.:|.|..:      ..||    
Mouse   145 QKKDNSQ-SPSQMDQFCKDHGFTGWFETSAKDNINIDEATRFLVENMLANQ------QSFPSEEI 202

  Fly   188 --DQITLGSQNNRPGNPDNCQC 207
              |:|.|..:  .|......||
Mouse   203 DLDRIKLVEE--PPTTKPRSQC 222

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Rab7NP_001247276.1 Rab7 9..179 CDD:206655 62/177 (35%)
RAB 9..174 CDD:197555 61/172 (35%)
Rab32NP_080681.1 Rab32_Rab38 24..222 CDD:206692 68/211 (32%)
RAB 24..193 CDD:197555 62/174 (36%)
Effector region. /evidence=ECO:0000250 52..60 5/7 (71%)
PKA-RII subunit binding domain. /evidence=ECO:0000250 176..195 5/24 (21%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

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