Protein Alignment Rab7 and RAP2B

DIOPT Version :9

• Sequence 1: NP_001247276.1
• Gene: Rab7 / 42841
• FlyBaseID: FBgn0015795
• Length: 207
• Species: Drosophila melanogaster
• Sequence 2: NP_002877.2
• Gene: RAP2B / 5912
• HGNCID: 9862
• Length: 183
• Species: Homo sapiens
• Alignment Length: 201
• Identity: 60/201 - (29%)
• Similarity: 98/201 - (48%)
• Gaps: 34/201 - (16%)

  Fly    10 KVIILGDSSVGKTSLMNQYVNKRFSNQYKATIGADFCTKEVVVNDRVVTMQIWDTAGQERFQSLG 74
            ||::||...|||::|..|:|...|..:|..|| .||..||:.|:.....::|.||||.|:|.|:.
Human     5 KVVVLGSGGVGKSALTVQFVTGSFIEKYDPTI-EDFYRKEIEVDSSPSVLEILDTAGTEQFASMR 68

  Fly    75 VAFYRGADCCVLVYDVTAPNSFKNLDSWRDEFLIQASPRDPDHFPFVVLGNKVDLD-NRQVS--- 135
            ..:.:.....:|||.:....||:::...||:.:   ..:..:..|.:::||||||: .|:||
Human    69 DLYIKNGQGFILVYSLVNQQSFQDIKPMRDQII---RVKRYERVPMILVGNKVDLEGEREVSYGE 130

  Fly   136 -TRRAQQWCQSKNDIPYYETSAKEGINVEMAFQVIAKNALELEAEAEVINDFPDQITLGSQNNRP 199
             ...|::|     ..|:.|||||...:|:..|             ||::.    |:...:|   |
Human   131 GKALAEEW-----SCPFMETSAKNKASVDELF-------------AEIVR----QMNYAAQ---P 170

  Fly   200 GNPDNC 205
            ...:.|
Human   171 NGDEGC 176

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rab7	NP_001247276.1	Rab7	9..179	CDD:206655	54/173 (31%)
		RAB	9..174	CDD:197555	54/168 (32%)
RAP2B	NP_002877.2	Rap2	3..165	CDD:133376	57/185 (31%)
		Effector region. /evidence=ECO:0000305	32..40		4/8 (50%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910