DRSC/TRiP Functional Genomics Resources

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Protein Alignment Rab7 and RAP2A

DIOPT Version :9

Sequence 1:NP_001247276.1 Gene:Rab7 / 42841 FlyBaseID:FBgn0015795 Length:207 Species:Drosophila melanogaster
Sequence 2:NP_066361.1 Gene:RAP2A / 5911 HGNCID:9861 Length:183 Species:Homo sapiens


Alignment Length:202 Identity:62/202 - (30%)
Similarity:100/202 - (49%) Gaps:36/202 - (17%)


- Green bases have known domain annotations that are detailed below.


  Fly    10 KVIILGDSSVGKTSLMNQYVNKRFSNQYKATIGADFCTKEVVVNDRVVTMQIWDTAGQERFQSLG 74
            ||::||...|||::|..|:|...|..:|..|| .||..||:.|:.....::|.||||.|:|.|:.
Human     5 KVVVLGSGGVGKSALTVQFVTGTFIEKYDPTI-EDFYRKEIEVDSSPSVLEILDTAGTEQFASMR 68

  Fly    75 VAFYRGADCCVLVYDVTAPNSFKNLDSWRDEFLIQASPRDPDHFPFVVLGNKVDLDN-RQVSTRR 138
            ..:.:.....:|||.:....||:::...||:.:   ..:..:..|.:::||||||:: |:||:..
Human    69 DLYIKNGQGFILVYSLVNQQSFQDIKPMRDQII---RVKRYEKVPVILVGNKVDLESEREVSSSE 130

  Fly   139 ----AQQW-CQSKNDIPYYETSAKEGINVEMAFQVIAKNALELEAEAEVINDFPDQITLGSQNNR 198
                |::| |      |:.|||||....|:..|             ||::.    |:...:|   
Human   131 GRALAEEWGC------PFMETSAKSKTMVDELF-------------AEIVR----QMNYAAQ--- 169

  Fly   199 PGNPDNC 205
            |...|.|
Human   170 PDKDDPC 176

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Rab7NP_001247276.1 Rab7 9..179 CDD:206655 55/174 (32%)
RAB 9..174 CDD:197555 55/169 (33%)
RAP2ANP_066361.1 Rap2 3..165 CDD:133376 58/186 (31%)
Effector region. /evidence=ECO:0000305 32..40 4/8 (50%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.910

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