DRSC/TRiP Functional Genomics Resources

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Protein Alignment Rab7 and RAN

DIOPT Version :9

Sequence 1:NP_001247276.1 Gene:Rab7 / 42841 FlyBaseID:FBgn0015795 Length:207 Species:Drosophila melanogaster
Sequence 2:XP_016875261.1 Gene:RAN / 5901 HGNCID:9846 Length:222 Species:Homo sapiens


Alignment Length:193 Identity:56/193 - (29%)
Similarity:98/193 - (50%) Gaps:17/193 - (8%)


- Green bases have known domain annotations that are detailed below.


  Fly     3 GRKKSLLKVIILGDSSVGKTSLMNQYVNKRFSNQYKATIGADFCTKEVVVNDRVVTMQIWDTAGQ 67
            |..:...|::::||...|||:.:.:::...|..:|.||:|.:........|...:...:||||||
Human     5 GEPQVQFKLVLVGDGGTGKTTFVKRHLTGEFEKKYVATLGVEVHPLVFHTNRGPIKFNVWDTAGQ 69

  Fly    68 ERFQSLGVAFYRGADCCVLVYDVTAPNSFKNLDSWRDEFLIQASPRDPDHFPFVVLGNKVDLDNR 132
            |:|..|...:|..|.|.::::|||:..::||:.:|..:.:     |..::.|.|:.|||||:.:|
Human    70 EKFGGLRDGYYIQAQCAIIMFDVTSRVTYKNVPNWHRDLV-----RVCENIPIVLCGNKVDIKDR 129

  Fly   133 QVSTRRAQQWCQSKNDIPYYETSAKEGINVEMAFQVIAKN----------ALELEAEAEVIND 185
            :|..:...  ...|.::.||:.|||...|.|..|..:|:.          |:...|..||:.|
Human   130 KVKAKSIV--FHRKKNLQYYDISAKSNYNFEKPFLWLARKLIGDPNLEFVAMPALAPPEVVMD 190

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Rab7NP_001247276.1 Rab7 9..179 CDD:206655 51/179 (28%)
RAB 9..174 CDD:197555 50/174 (29%)
RANXP_016875261.1 None


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.910

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