Protein Alignment Rab7 and RAB5C

DIOPT Version :9

• Sequence 1: NP_001247276.1
• Gene: Rab7 / 42841
• FlyBaseID: FBgn0015795
• Length: 207
• Species: Drosophila melanogaster
• Sequence 2: NP_001238968.1
• Gene: RAB5C / 5878
• HGNCID: 9785
• Length: 249
• Species: Homo sapiens
• Alignment Length: 213
• Identity: 76/213 - (35%)
• Similarity: 111/213 - (52%)
• Gaps: 23/213 - (10%)

  Fly     2 SGRKKSLLKVIILGDSSVGKTSLMNQYVNKRFSNQYKATIGADFCTKEVVVNDRVVTMQIWDTAG 66
            :|.|....|:::||:|:|||:||:.::|..:|....::||||.|.|:.|.::|..|..:||||||
Human    48 AGNKICQFKLVLLGESAVGKSSLVLRFVKGQFHEYQESTIGAAFLTQTVCLDDTTVKFEIWDTAG 112

  Fly    67 QERFQSLGVAFYRGADCCVLVYDVTAPNSFKNLDSWRDEFLIQASPRDPDHFPFVVLGNKVDL-D 130
            |||:.||...:||||...::|||:|..::|....:|..|...||||    :....:.|||.|| .
Human   113 QERYHSLAPMYYRGAQAAIVVYDITNTDTFARAKNWVKELQRQASP----NIVIALAGNKADLAS 173

  Fly   131 NRQVSTRRAQQWCQSKNDIPYYETSAKEGINVEMAFQVIAKNALELEAEAEVINDFPDQIT---- 191
            .|.|..:.||.:... |.:.:.|||||..:||...|..|||...:.|         |...|
Human   174 KRAVEFQEAQAYADD-NSLLFMETSAKTAMNVNEIFMAIAKKLPKNE---------PQNATGAPG 228

  Fly   192 ----LGSQNNRPGNPDNC 205
                :..|.|.|.:...|
Human   229 RNRGVDLQENNPASRSQC 246

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rab7	NP_001247276.1	Rab7	9..179	CDD:206655	68/170 (40%)
		RAB	9..174	CDD:197555	67/165 (41%)
RAB5C	NP_001238968.1	Rab5_related	54..216	CDD:206653	67/166 (40%)
		Ras	56..217	CDD:278499	67/165 (41%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910