Protein Alignment Rab7 and RAB27B

DIOPT Version :9

• Sequence 1: NP_001247276.1
• Gene: Rab7 / 42841
• FlyBaseID: FBgn0015795
• Length: 207
• Species: Drosophila melanogaster
• Sequence 2: NP_001362256.1
• Gene: RAB27B / 5874
• HGNCID: 9767
• Length: 218
• Species: Homo sapiens
• Alignment Length: 214
• Identity: 79/214 - (36%)
• Similarity: 121/214 - (56%)
• Gaps: 18/214 - (8%)

  Fly     8 LLKVIILGDSSVGKTSLMNQYVNKRFSNQYKATIGADFCTKEVVVNDR----------VVTMQIW 62
            |:|::.||||.||||:.:.:|.:.:|:.::..|:|.||..|.||.|.:          .|.:|:|
Human     9 LIKLLALGDSGVGKTTFLYRYTDNKFNPKFITTVGIDFREKRVVYNAQGPNGSSGKAFKVHLQLW 73

  Fly    63 DTAGQERFQSLGVAFYRGADCCVLVYDVTAPNSFKNLDSWRDEFLIQASPRDPDHFPFVVLGNKV 127
            ||||||||:||..||:|.|...:|::|:|:..||.|:.:|..:....|...:||   .|::|||.
Human    74 DTAGQERFRSLTTAFFRDAMGFLLMFDLTSQQSFLNVRNWMSQLQANAYCENPD---IVLIGNKA 135

  Fly   128 DL-DNRQVSTRRAQQWCQSKNDIPYYETSAKEGINVEMAFQVIAKNALELEAEAEVINDFPDQIT 191
            || |.|:|:.|:|:: ...|..|||:||||..|.|||.|.:.:....::...:.......||.:.
Human   136 DLPDQREVNERQARE-LADKYGIPYFETSAATGQNVEKAVETLLDLIMKRMEQCVEKTQIPDTVN 199

  Fly   192 LGSQNNRPGN--PD-NCQC 207
            .|:..|..|.  |: .|.|
Human   200 GGNSGNLDGEKPPEKKCIC 218

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rab7	NP_001247276.1	Rab7	9..179	CDD:206655	70/180 (39%)
		RAB	9..174	CDD:197555	70/175 (40%)
RAB27B	NP_001362256.1	Rab27A	6..185	CDD:206700	71/179 (40%)
		Effector region. /evidence=ECO:0000250	38..46		2/7 (29%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	194..218		7/23 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910