DRSC/TRiP Functional Genomics Resources

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Protein Alignment Rab7 and RAB13

DIOPT Version :9

Sequence 1:NP_001247276.1 Gene:Rab7 / 42841 FlyBaseID:FBgn0015795 Length:207 Species:Drosophila melanogaster
Sequence 2:NP_002861.1 Gene:RAB13 / 5872 HGNCID:9762 Length:203 Species:Homo sapiens


Alignment Length:195 Identity:70/195 - (35%)
Similarity:111/195 - (56%) Gaps:23/195 - (11%)


- Green bases have known domain annotations that are detailed below.


  Fly     8 LLKVIILGDSSVGKTSLMNQYVNKRFSNQYKATIGADFCTKEVVVNDRVVTMQIWDTAGQERFQS 72
            |.|::::|||.||||.|:.::....|:|.|.:|||.||..:.|.:..:.:.:|:|||||||||::
Human     8 LFKLLLIGDSGVGKTCLIIRFAEDNFNNTYISTIGIDFKIRTVDIEGKKIKLQVWDTAGQERFKT 72

  Fly    73 LGVAFYRGADCCVLVYDVTAPNSFKNLDSWRDEFLIQASPRDPDHFPFVVLGNKVDLD-NRQVST 136
            :..|:||||...:||||:|...||:|:.:|.......||.    ....::||||.|:: .|:|..
Human    73 ITTAYYRGAMGIILVYDITDEKSFENIQNWMKSIKENASA----GVERLLLGNKCDMEAKRKVQK 133

  Fly   137 RRAQQWCQSKNDIPYYETSAKEGINVEMAFQVIAKNALELEAEAEVINDFPDQITLGSQNNRPGN 201
            .:|.:..: ::.|.::|||||..:||:.||..:|::                 |.|.|...|.||
Human   134 EQADKLAR-EHGIRFFETSAKSSMNVDEAFSSLARD-----------------ILLKSGGRRSGN 180

  Fly   202  201
            Human   181  180

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Rab7NP_001247276.1 Rab7 9..179 CDD:206655 63/170 (37%)
RAB 9..174 CDD:197555 63/165 (38%)
RAB13NP_002861.1 Rab8_Rab10_Rab13_like 6..172 CDD:206659 65/185 (35%)
Effector region. /evidence=ECO:0000250 37..45 4/7 (57%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 173..203 4/8 (50%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.910

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