DRSC/TRiP Functional Genomics Resources

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Protein Alignment Rab7 and RAB3B

DIOPT Version :9

Sequence 1:NP_001247276.1 Gene:Rab7 / 42841 FlyBaseID:FBgn0015795 Length:207 Species:Drosophila melanogaster
Sequence 2:NP_002858.2 Gene:RAB3B / 5865 HGNCID:9778 Length:219 Species:Homo sapiens


Alignment Length:208 Identity:69/208 - (33%)
Similarity:112/208 - (53%) Gaps:18/208 - (8%)


- Green bases have known domain annotations that are detailed below.


  Fly     8 LLKVIILGDSSVGKTSLMNQYVNKRFSNQYKATIGADFCTKEVVVNDRVVTMQIWDTAGQERFQS 72
            :.|::|:|:|||||||.:.:|.:..|:..:.:|:|.||..|.|..:::.|.:||||||||||:::
Human    22 MFKLLIIGNSSVGKTSFLFRYADDTFTPAFVSTVGIDFKVKTVYRHEKRVKLQIWDTAGQERYRT 86

  Fly    73 LGVAFYRGADCCVLVYDVTAPNSFKNLDSWRDEFLIQASPRDPDHFPFVVLGNKVDLDNRQVSTR 137
            :..|:||||...:|:||:|...||..:..|    ..|......|:...:::|||.|::..:|...
Human    87 ITTAYYRGAMGFILMYDITNEESFNAVQDW----ATQIKTYSWDNAQVILVGNKCDMEEERVVPT 147

  Fly   138 RAQQWCQSKNDIPYYETSAKEGINVEMAFQVIAKNALELEAEAEVINDF--PDQITLGSQNNR-- 198
            ...|....:....::|.||||.|:|..||:.:      ::|..:.::|.  .|...|||..|.  
Human   148 EKGQLLAEQLGFDFFEASAKENISVRQAFERL------VDAICDKMSDSLDTDPSMLGSSKNTRL 206

  Fly   199 ----PGNPDNCQC 207
                |....||.|
Human   207 SDTPPLLQQNCSC 219

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Rab7NP_001247276.1 Rab7 9..179 CDD:206655 58/169 (34%)
RAB 9..174 CDD:197555 58/164 (35%)
RAB3BNP_002858.2 Rab3 22..186 CDD:206657 59/173 (34%)
RAB 23..183 CDD:197555 58/169 (34%)
Effector region. /evidence=ECO:0000250 51..59 2/7 (29%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.910

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