Protein Alignment Rab7 and RAB2A

DIOPT Version :10

• Sequence 1: NP_524472.1
• Gene: Rab7 / 42841
• FlyBaseID: FBgn0015795
• Length: 207
• Species: Drosophila melanogaster
• Sequence 2: NP_002856.1
• Gene: RAB2A / 5862
• HGNCID: 9763
• Length: 212
• Species: Homo sapiens
• Alignment Length: 190
• Identity: 67/190 - (35%)
• Similarity: 111/190 - (58%)
• Gaps: 5/190 - (2%)

  Fly     8 LLKVIILGDSSVGKTSLMNQYVNKRFSNQYKATIGADFCTKEVVVNDRVVTMQIWDTAGQERFQS 72
            |.|.||:||:.|||:.|:.|:.:|||...:..|||.:|..:.:.::.:.:.:|||||||||.|:|
Human     6 LFKYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMITIDGKQIKLQIWDTAGQESFRS 70

  Fly    73 LGVAFYRGADCCVLVYDVTAPNSFKNLDSWRDEFLIQASPRDPDHFPFVVLGNKVDLDNRQVSTR 137
            :..::||||...:||||:|..::|.:|.:|.::    |......:...:::|||.||::|:...:
Human    71 ITRSYYRGAAGALLVYDITRRDTFNHLTTWLED----ARQHSNSNMVIMLIGNKSDLESRREVKK 131

  Fly   138 RAQQWCQSKNDIPYYETSAKEGINVEMAFQVIAKNALELEAEAEV-INDFPDQITLGSQN 196
            ...:....::.:.:.|||||...|||.||...||...|...|... ||:..:.|.:|.|:
Human   132 EEGEAFAREHGLIFMETSAKTASNVEEAFINTAKEIYEKIQEGVFDINNEANGIKIGPQH 191

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rab7	NP_524472.1	Rab7	9..179	CDD:206655	60/169 (36%)
RAB2A	NP_002856.1	PLN03108	1..188	CDD:178655	65/185 (35%)
		Required for interaction with PRKCI. /evidence=ECO:0000269|PubMed:14570876	2..19		7/12 (58%)
		Switch 1. /evidence=ECO:0000250|UniProtKB:P61106	37..42		3/4 (75%)
		Switch 2. /evidence=ECO:0000250|UniProtKB:P61106	63..72		6/8 (75%)