DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rab7 and cracr2ab

DIOPT Version :9

Sequence 1:	NP_001247276.1	Gene:	Rab7 / 42841	FlyBaseID:	FBgn0015795	Length:	207	Species:	Drosophila melanogaster
Sequence 2:	XP_009298523.1	Gene:	cracr2ab / 564347	ZFINID:	ZDB-GENE-041210-94	Length:	773	Species:	Danio rerio

Alignment Length:	189	Identity:	71/189 - (37%)
Similarity:	111/189 - (58%)	Gaps:	11/189 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 LLKVIILGDSSVGKTSLMNQYVNKRFSNQYKATIGADFCTKEVVVNDRVVTMQIWDTAGQERFQS 72
            |.|||::|:||||||:|:.::.:.:|.:...||:|.|:..:.:.:.|..|.:|:||||||||::|
Zfish   586 LFKVILVGNSSVGKTALLRRFCDGQFHSATSATVGIDYSVRTLNLGDSHVALQLWDTAGQERYRS 650

  Fly    73 LGVAFYRGADCCVLVYDVTAPNSFKNLDSWRDEFLIQASPRDPDHFPFVVLGNKVDLDN-RQVST 136
            :...|:|.||..|::||:|..:||.::..|...  ||.:..||  .|.::||||.|.:| |:|.|
Zfish   651 ITKQFFRKADGVVVIYDITMEDSFSSVRPWLSS--IQEAVGDP--IPVMLLGNKSDKENEREVQT 711

  Fly   137 RRAQQWCQSKNDIPYYETSAKEGINVEMAFQVIAKNALELEAEAEVINDFPDQITLGSQ 195
            :.|....:..| :.:||.||..|.||..|...:|:...|.|....|     :.:.||.|
Zfish   712 KEADLLAEEAN-LMFYECSAYTGANVLEAMIHLARVLREQEDRVWV-----NTVRLGDQ 764

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rab7	NP_001247276.1	Rab7	9..179	CDD:206655	66/170 (39%)
Rab7	NP_001247276.1	RAB	9..174	CDD:197555	64/165 (39%)
cracr2ab	XP_009298523.1	EFh	46..106	CDD:238008
		EF-hand_7	47..98	CDD:290234
		FAM184	210..390	CDD:292293
		RAB	587..745	CDD:197555	63/162 (39%)
		Rab	587..745	CDD:206640	63/162 (39%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.910