DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rab7 and rab3ab

DIOPT Version :9

Sequence 1:	NP_001247276.1	Gene:	Rab7 / 42841	FlyBaseID:	FBgn0015795	Length:	207	Species:	Drosophila melanogaster
Sequence 2:	NP_001017761.1	Gene:	rab3ab / 550457	ZFINID:	ZDB-GENE-041210-268	Length:	220	Species:	Danio rerio

Alignment Length:	219	Identity:	73/219 - (33%)
Similarity:	120/219 - (54%)	Gaps:	22/219 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 GRKKS-------LLKVIILGDSSVGKTSLMNQYVNKRFSNQYKATIGADFCTKEVVVNDRVVTMQ 60
            |:|:|       :.|::|:|:|||||||.:.:|.:..|:..:.:|:|.||..|.:..||:.:.:|
Zfish    10 GQKESSDQNFDYMFKILIIGNSSVGKTSFLFRYADDSFTPAFVSTVGIDFKVKTIYRNDKRIKLQ 74

  Fly    61 IWDTAGQERFQSLGVAFYRGADCCVLVYDVTAPNSFKNLDSWRDEFLIQASPRDPDHFPFVVLGN 125
            |||||||||::::..|:||||...:|:||:|...||..:..|.    .|......|:...:::||
Zfish    75 IWDTAGQERYRTITTAYYRGAMGFILMYDITNEESFAAVQDWS----TQIKTYSWDNAQVLLVGN 135

  Fly   126 KVDL-DNRQVSTRRAQQWCQSKNDIPYYETSAKEGINVEMAFQVIAKNALELEAEAEVINDFPDQ 189
            |.|: |.|.|::.|.:|..:... ..|:|.|||:.|||:..|:.:.....|..:|:   .|..|.
Zfish   136 KCDMEDERVVASERGRQLSEHLG-FEYFEASAKDNINVKQTFERLVDIICEKMSES---LDAADP 196

  Fly   190 ITLGSQ-----NNRPGNP-DNCQC 207
            ...|::     ..:|..| .:|.|
Zfish   197 AVTGAKQGPQLTEQPAAPHQDCAC 220

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rab7	NP_001247276.1	Rab7	9..179	CDD:206655	62/170 (36%)
Rab7	NP_001247276.1	RAB	9..174	CDD:197555	61/165 (37%)
rab3ab	NP_001017761.1	Rab3	22..186	CDD:206657	61/168 (36%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.910