Protein Alignment Rab7 and RAB8B

DIOPT Version :10

• Sequence 1: NP_524472.1
• Gene: Rab7 / 42841
• FlyBaseID: FBgn0015795
• Length: 207
• Species: Drosophila melanogaster
• Sequence 2: NP_057614.1
• Gene: RAB8B / 51762
• HGNCID: 30273
• Length: 207
• Species: Homo sapiens
• Alignment Length: 168
• Identity: 67/168 - (39%)
• Similarity: 103/168 - (61%)
• Gaps: 6/168 - (3%)

  Fly     8 LLKVIILGDSSVGKTSLMNQYVNKRFSNQYKATIGADFCTKEVVVNDRVVTMQIWDTAGQERFQS 72
            |.|::::|||.||||.|:.::....|:..:.:|||.||..:.:.::.:.:.:|||||||||||::
Human     8 LFKLLLIGDSGVGKTCLLFRFSEDAFNTTFISTIGIDFKIRTIELDGKKIKLQIWDTAGQERFRT 72

  Fly    73 LGVAFYRGADCCVLVYDVTAPNSFKNLDSWRDEFLIQASPRDPDHFPFVVLGNKVDL-DNRQVST 136
            :..|:||||...:||||:|...||.|:.:|.......|| .|.:.   ::||||.|: |.||||.
Human    73 ITTAYYRGAMGIMLVYDITNEKSFDNIKNWIRNIEEHAS-SDVER---MILGNKCDMNDKRQVSK 133

  Fly   137 RRAQQWCQSKNDIPYYETSAKEGINVEMAFQVIAKNAL 174
            .|.::...... |.:.|||||...|||.||..:|::.:
Human   134 ERGEKLAIDYG-IKFLETSAKSSANVEEAFFTLARDIM 170

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rab7	NP_524472.1	Rab7	9..179	CDD:206655	66/167 (40%)
RAB8B	NP_057614.1	Rab8_Rab10_Rab13_like	6..172	CDD:206659	67/168 (40%)
		Switch 1. /evidence=ECO:0000250|UniProtKB:P62820	31..45		4/13 (31%)
		Switch 2. /evidence=ECO:0000250|UniProtKB:P62820	63..80		10/16 (63%)