DRSC/TRiP Functional Genomics Resources

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Protein Alignment Rab7 and RAB6B

DIOPT Version :9

Sequence 1:NP_001247276.1 Gene:Rab7 / 42841 FlyBaseID:FBgn0015795 Length:207 Species:Drosophila melanogaster
Sequence 2:NP_057661.3 Gene:RAB6B / 51560 HGNCID:14902 Length:208 Species:Homo sapiens


Alignment Length:199 Identity:74/199 - (37%)
Similarity:112/199 - (56%) Gaps:6/199 - (3%)


- Green bases have known domain annotations that are detailed below.


  Fly    10 KVIILGDSSVGKTSLMNQYVNKRFSNQYKATIGADFCTKEVVVNDRVVTMQIWDTAGQERFQSLG 74
            |::.||:.|||||||:.:::...|.|.|:||||.||.:|.:.:.||.|.:|:|||||||||:||.
Human    15 KLVFLGEQSVGKTSLITRFMYDSFDNTYQATIGIDFLSKTMYLEDRTVRLQLWDTAGQERFRSLI 79

  Fly    75 VAFYRGADCCVLVYDVTAPNSFKNLDSWRDEFLIQASPRDPDHFPFVVLGNKVDL-DNRQVSTRR 138
            .::.|.:...|:|||:|..|||:....|.|:.   .:.|..|.. .:::|||.|| |.||::...
Human    80 PSYIRDSTVAVVVYDITNLNSFQQTSKWIDDV---RTERGSDVI-IMLVGNKTDLADKRQITIEE 140

  Fly   139 AQQWCQSKNDIPYYETSAKEGINVEMAFQVIAKNALELEAEAEVINDFPDQITLGSQNNRPGNPD 203
            .:|..:..: :.:.|||||.|.||:..|:.:|.....:|...|...:....|.|......|.:..
Human   141 GEQRAKELS-VMFIETSAKTGYNVKQLFRRVASALPGMENVQEKSKEGMIDIKLDKPQEPPASEG 204

  Fly   204 NCQC 207
            .|.|
Human   205 GCSC 208

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Rab7NP_001247276.1 Rab7 9..179 CDD:206655 68/169 (40%)
RAB 9..174 CDD:197555 67/164 (41%)
RAB6BNP_057661.3 Rab6 14..174 CDD:206654 67/163 (41%)
Effector region. /evidence=ECO:0000250 42..50 5/7 (71%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.910

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