DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rab7 and RAB9B

DIOPT Version :9

Sequence 1:	NP_001247276.1	Gene:	Rab7 / 42841	FlyBaseID:	FBgn0015795	Length:	207	Species:	Drosophila melanogaster
Sequence 2:	NP_057454.1	Gene:	RAB9B / 51209	HGNCID:	14090	Length:	201	Species:	Homo sapiens

Alignment Length:	181	Identity:	99/181 - (54%)
Similarity:	128/181 - (70%)	Gaps:	1/181 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MSGRKKSLLKVIILGDSSVGKTSLMNQYVNKRFSNQYKATIGADFCTKEVVVNDRVVTMQIWDTA 65
            ||| |..|||||:|||..|||:||||:||..:|.:|...|||.:|..:::.|:.|.||:||||||
Human     1 MSG-KSLLLKVILLGDGGVGKSSLMNRYVTNKFDSQAFHTIGVEFLNRDLEVDGRFVTLQIWDTA 64

  Fly    66 GQERFQSLGVAFYRGADCCVLVYDVTAPNSFKNLDSWRDEFLIQASPRDPDHFPFVVLGNKVDLD 130
            |||||:||...||||||||:|.:.|....||:||.:|:.||:..|..:||:||||||||||||.:
Human    65 GQERFKSLRTPFYRGADCCLLTFSVDDRQSFENLGNWQKEFIYYADVKDPEHFPFVVLGNKVDKE 129

  Fly   131 NRQVSTRRAQQWCQSKNDIPYYETSAKEGINVEMAFQVIAKNALELEAEAE 181
            :|||:|..||.||....|.||.|||||:..||.:||:...:..|.:|.:.|
Human   130 DRQVTTEEAQTWCMENGDYPYLETSAKDDTNVTVAFEEAVRQVLAVEEQLE 180

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rab7	NP_001247276.1	Rab7	9..179	CDD:206655	93/169 (55%)
Rab7	NP_001247276.1	RAB	9..174	CDD:197555	91/164 (55%)
RAB9B	NP_057454.1	Rab9	3..172	CDD:206697	94/169 (56%)
RAB9B	NP_057454.1	Effector region. /evidence=ECO:0000250	36..44		3/7 (43%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0394
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810