DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rab7 and ran

DIOPT Version :9

Sequence 1:	NP_001247276.1	Gene:	Rab7 / 42841	FlyBaseID:	FBgn0015795	Length:	207	Species:	Drosophila melanogaster
Sequence 2:	NP_001004829.1	Gene:	ran / 448091	XenbaseID:	XB-GENE-489468	Length:	216	Species:	Xenopus tropicalis

Alignment Length:	193	Identity:	56/193 - (29%)
Similarity:	98/193 - (50%)	Gaps:	17/193 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 GRKKSLLKVIILGDSSVGKTSLMNQYVNKRFSNQYKATIGADFCTKEVVVNDRVVTMQIWDTAGQ 67
            |..:...|::::||...|||:.:.:::...|..:|.||:|.:........|...:...:||||||
Frog     5 GEPQVQFKLVLVGDGGTGKTTFVKRHLTGEFEKKYVATLGVEVHPLVFHTNRGPIKFNVWDTAGQ 69

  Fly    68 ERFQSLGVAFYRGADCCVLVYDVTAPNSFKNLDSWRDEFLIQASPRDPDHFPFVVLGNKVDLDNR 132
            |:|..|...:|..|.|.::::|||:..::||:.:|..:.:     |..::.|.|:.|||||:.:|
Frog    70 EKFGGLRDGYYIQAQCAIIMFDVTSRVTYKNVPNWHRDLV-----RVCENIPIVLCGNKVDIKDR 129

  Fly   133 QVSTRRAQQWCQSKNDIPYYETSAKEGINVEMAFQVIAKN----------ALELEAEAEVIND 185
            :|..:...  ...|.::.||:.|||...|.|..|..:|:.          |:...|..||:.|
Frog   130 KVKAKSIV--FHRKKNLQYYDISAKSNYNFEKPFLWLARKLIGDPNFEFVAMPALAPPEVVMD 190

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rab7	NP_001247276.1	Rab7	9..179	CDD:206655	51/179 (28%)
Rab7	NP_001247276.1	RAB	9..174	CDD:197555	50/174 (29%)
ran	NP_001004829.1	PTZ00132	1..216	CDD:240284	56/193 (29%)
ran	NP_001004829.1	Interaction with RANBP1. /evidence=ECO:0000250\|UniProtKB:P62826	211..216
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910