DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment Rab7 and rab3db

DIOPT Version :9

Sequence 1:NP_001247276.1 Gene:Rab7 / 42841 FlyBaseID:FBgn0015795 Length:207 Species:Drosophila melanogaster
Sequence 2:XP_005168533.1 Gene:rab3db / 436952 ZFINID:ZDB-GENE-040718-428 Length:231 Species:Danio rerio


Alignment Length:183 Identity:64/183 - (34%)
Similarity:107/183 - (58%) Gaps:11/183 - (6%)


- Green bases have known domain annotations that are detailed below.


  Fly     8 LLKVIILGDSSVGKTSLMNQYVNKRFSNQYKATIGADFCTKEVVVNDRVVTMQIWDTAGQERFQS 72
            :.|::|:|:|||||||.:.:|.:..|::.:.:|:|.||..|.|..|::.:.:||||||||||:::
Zfish    35 MFKLLIIGNSSVGKTSFLFRYADDSFTSAFVSTVGIDFKVKTVFRNNKRIKLQIWDTAGQERYRT 99

  Fly    73 LGVAFYRGADCCVLVYDVTAPNSFKNLDSWRDEFLIQASPRDPDHFPFVVLGNKVDL-DNRQVST 136
            :..|:||||...:|::|:|..:||..:..|    ..|......|:...:::|||.|| |.|.:.|
Zfish   100 ITTAYYRGAMGFLLMFDITNRDSFNAVRDW----ATQIKTYSWDNAQVILVGNKCDLEDERLIPT 160

  Fly   137 RRAQQWCQSKNDIPYYETSAKEGINVEMAFQVIA-----KNALELEAEAEVIN 184
            ..:|:...... ..::|.|||:.|||:..|:.:.     |....|:.:|.|.|
Zfish   161 EDSQRLAHELG-FQFFEASAKDSINVKQVFECLVDVICDKMTESLDGDAAVSN 212

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Rab7NP_001247276.1 Rab7 9..179 CDD:206655 61/175 (35%)
RAB 9..174 CDD:197555 60/170 (35%)
rab3dbXP_005168533.1 P-loop_NTPase 35..199 CDD:304359 59/168 (35%)
RAB 36..196 CDD:197555 59/164 (36%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
21.910

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