DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rab7 and rab7b

DIOPT Version :9

Sequence 1:	NP_001247276.1	Gene:	Rab7 / 42841	FlyBaseID:	FBgn0015795	Length:	207	Species:	Drosophila melanogaster
Sequence 2:	NP_001002178.1	Gene:	rab7b / 431725	ZFINID:	ZDB-GENE-180906-1	Length:	204	Species:	Danio rerio

Alignment Length:	208	Identity:	162/208 - (77%)
Similarity:	181/208 - (87%)	Gaps:	5/208 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MSGRKKSLLKVIILGDSSVGKTSLMNQYVNKRFSNQYKATIGADFCTKEVVVNDRVVTMQIWDTA 65
            |:.|||.||||||||||.||||||||||||.:|||||||||||||.||||:|:||:|||||||||
Zfish     1 MASRKKVLLKVIILGDSGVGKTSLMNQYVNNKFSNQYKATIGADFLTKEVMVDDRLVTMQIWDTA 65

  Fly    66 GQERFQSLGVAFYRGADCCVLVYDVTAPNSFKNLDSWRDEFLIQASPRDPDHFPFVVLGNKVDLD 130
            ||||||||||||||||||||||||||||.:||.|||||||||||||..||::|||||||||:|||
Zfish    66 GQERFQSLGVAFYRGADCCVLVYDVTAPTTFKTLDSWRDEFLIQASTSDPENFPFVVLGNKIDLD 130

  Fly   131 NRQVSTRRAQQWCQSKNDIPYYETSAKEGINVEMAFQVIAKNALELEAEAEVINDFPDQITLGSQ 195
            ||||||:|||.||||||:|||:||||||.||||.|||.||:|||:.|:..:.  ||||:|.||
Zfish   131 NRQVSTKRAQAWCQSKNNIPYFETSAKEAINVEQAFQTIARNALKQESVDKY--DFPDEIKLG-- 191

  Fly   196 NNRP-GNPDNCQC 207
            |:|| .|.:.|.|
Zfish   192 NDRPMSNGEGCSC 204

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rab7	NP_001247276.1	Rab7	9..179	CDD:206655	144/169 (85%)
Rab7	NP_001247276.1	RAB	9..174	CDD:197555	141/164 (86%)
rab7b	NP_001002178.1	Rab7	9..178	CDD:206655	143/168 (85%)
rab7b	NP_001002178.1	RAB	9..176	CDD:197555	143/166 (86%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170592696
Domainoid	1	1.000	302	1.000	Domainoid score	I1369
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H100564
Inparanoid	1	1.050	334	1.000	Inparanoid score	I2393
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1172019at2759
OrthoFinder	1	1.000	-	-		FOG0001661
OrthoInspector	1	1.000	-	-		otm25790
orthoMCL	1	0.900	-	-		OOG6_101358
Panther	1	1.100	-	-	O	PTHR47981
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1058
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	12	11.860