Protein Alignment Rab7 and RAB8A

DIOPT Version :9

• Sequence 1: NP_001247276.1
• Gene: Rab7 / 42841
• FlyBaseID: FBgn0015795
• Length: 207
• Species: Drosophila melanogaster
• Sequence 2: NP_005361.2
• Gene: RAB8A / 4218
• HGNCID: 7007
• Length: 207
• Species: Homo sapiens
• Alignment Length: 197
• Identity: 72/197 - (36%)
• Similarity: 116/197 - (58%)
• Gaps: 11/197 - (5%)

  Fly     8 LLKVIILGDSSVGKTSLMNQYVNKRFSNQYKATIGADFCTKEVVVNDRVVTMQIWDTAGQERFQS 72
            |.|::::|||.||||.::.::....|::.:.:|||.||..:.:.::.:.:.:|||||||||||::
Human     8 LFKLLLIGDSGVGKTCVLFRFSEDAFNSTFISTIGIDFKIRTIELDGKRIKLQIWDTAGQERFRT 72

  Fly    73 LGVAFYRGADCCVLVYDVTAPNSFKNLDSWRDEFLIQASPRDPDHFPFVVLGNKVDL-DNRQVST 136
            :..|:||||...:||||:|...||.|:.:|.......|| .|.:.   ::||||.|: |.||||.
Human    73 ITTAYYRGAMGIMLVYDITNEKSFDNIRNWIRNIEEHAS-ADVEK---MILGNKCDVNDKRQVSK 133

  Fly   137 RRAQQWCQSKNDIPYYETSAKEGINVEMAFQVIAKNALELEAEAEVINDFPDQITLGSQNNRPGN 201
            .|.::...... |.:.|||||..||||.||..:|:: ::.:.:.::..:.|.    ||.......
Human   134 ERGEKLALDYG-IKFMETSAKANINVENAFFTLARD-IKAKMDKKLEGNSPQ----GSNQGVKIT 192

  Fly   202 PD 203
            ||
Human   193 PD 194

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rab7	NP_001247276.1	Rab7	9..179	CDD:206655	66/170 (39%)
		RAB	9..174	CDD:197555	66/165 (40%)
RAB8A	NP_005361.2	Rab8_Rab10_Rab13_like	6..172	CDD:206659	67/169 (40%)
		Effector region. /evidence=ECO:0000250	37..45		3/7 (43%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910