DRSC/TRiP Functional Genomics Resources

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Protein Alignment Rab7 and RAB15

DIOPT Version :9

Sequence 1:NP_001247276.1 Gene:Rab7 / 42841 FlyBaseID:FBgn0015795 Length:207 Species:Drosophila melanogaster
Sequence 2:NP_001295083.1 Gene:RAB15 / 376267 HGNCID:20150 Length:212 Species:Homo sapiens


Alignment Length:215 Identity:65/215 - (30%)
Similarity:115/215 - (53%) Gaps:25/215 - (11%)


- Green bases have known domain annotations that are detailed below.


  Fly     8 LLKVIILGDSSVGKTSLMNQYVNKRFSNQYKATIGADFCTKEVVVNDRVVTMQIWDTAGQERFQS 72
            |.:::::|||.||||.|:.::.:..|.:.:.:|||.||..|.:.|:...|.:||||||||||:|:
Human     8 LFRLLLIGDSGVGKTCLLCRFTDNEFHSSHISTIGVDFKMKTIEVDGIKVRIQIWDTAGQERYQT 72

  Fly    73 LGVAFYRGADCCVLVYDVTAPNSFKNLDSW---RDEFLIQASPRDPDHFPFVVLGNKVDLD-NRQ 133
            :...:||.|....||||:::..|::::..|   .||:.       |:....:::|||.|.: .||
Human    73 ITKQYYRRAQGIFLVYDISSERSYQHIMKWVSDVDEYA-------PEGVQKILIGNKADEEQKRQ 130

  Fly   134 VSTRRAQQWCQSKNDIPYYETSAKEGINVEMAFQVIAKNALELEAEAEVINDF----PDQITLGS 194
            |...:.||..: :..:.:|||||...:|::.:|..:.:  |.|:|..:.:...    .:::.|..
Human   131 VGREQGQQLAK-EYGMDFYETSACTNLNIKESFTRLTE--LVLQAHRKELEGLRMRASNELALAE 192

  Fly   195 QNNRPGNPD-------NCQC 207
            .....|.|:       .|.|
Human   193 LEEEEGKPEGPANSSKTCWC 212

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Rab7NP_001247276.1 Rab7 9..179 CDD:206655 58/173 (34%)
RAB 9..174 CDD:197555 56/168 (33%)
RAB15NP_001295083.1 Rab15 9..172 CDD:206698 58/172 (34%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 193..212 3/18 (17%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.910

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