DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rab7 and rab13

DIOPT Version :9

Sequence 1:	NP_001247276.1	Gene:	Rab7 / 42841	FlyBaseID:	FBgn0015795	Length:	207	Species:	Drosophila melanogaster
Sequence 2:	NP_958486.1	Gene:	rab13 / 373105	ZFINID:	ZDB-GENE-030826-30	Length:	200	Species:	Danio rerio

Alignment Length:	174	Identity:	64/174 - (36%)
Similarity:	107/174 - (61%)	Gaps:	4/174 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MSGRKKSLLKVIILGDSSVGKTSLMNQYVNKRFSNQYKATIGADFCTKEVVVNDRVVTMQIWDTA 65
            |:.:...|.|::::|||.||||.|:.::....|::.|.:|||.||..|.:.|..:.|.:|:||||
Zfish     1 MAKKYDFLFKLLLIGDSGVGKTCLIIRFAEDNFNSTYISTIGIDFKVKTIEVEGKKVKLQVWDTA 65

  Fly    66 GQERFQSLGVAFYRGADCCVLVYDVTAPNSFKNLDSWRDEFLIQASPRDPDHFPFVVLGNKVDLD 130
            |||||:::..|:||||...:||||:|...|::|:.:|.......||.    ....::||||.|::
Zfish    66 GQERFKTITTAYYRGAMGIILVYDITDEKSYENIQNWMKSIKENASA----GVSRMLLGNKCDIE 126

  Fly   131 NRQVSTRRAQQWCQSKNDIPYYETSAKEGINVEMAFQVIAKNAL 174
            .::..::...:....::.|.::|||||..||||.:|..:|::.|
Zfish   127 AKRKVSKETGEKLAKEHGIRFFETSAKSSINVEESFTSLARDIL 170

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rab7	NP_001247276.1	Rab7	9..179	CDD:206655	62/166 (37%)
Rab7	NP_001247276.1	RAB	9..174	CDD:197555	61/164 (37%)
rab13	NP_958486.1	Rab8_Rab10_Rab13_like	6..172	CDD:206659	63/169 (37%)
		RAB	9..170	CDD:197555	61/164 (37%)
		Effector region. /evidence=ECO:0000250	37..45		4/7 (57%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	173..195
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.910