Protein Alignment Rab7 and RAB7B

DIOPT Version :9

• Sequence 1: NP_001247276.1
• Gene: Rab7 / 42841
• FlyBaseID: FBgn0015795
• Length: 207
• Species: Drosophila melanogaster
• Sequence 2: NP_001157994.1
• Gene: RAB7B / 338382
• HGNCID: 30513
• Length: 199
• Species: Homo sapiens
• Alignment Length: 195
• Identity: 92/195 - (47%)
• Similarity: 127/195 - (65%)
• Gaps: 8/195 - (4%)

  Fly     1 MSGRKKSLLKVIILGDSSVGKTSLMNQYVNKRFSNQYKATIGADFCTKEVVVNDRVVTMQIWDTA 65
            |:.|||..||:||:|...||||||::|||:|.|..:|:.|:||...:|.:::.|..:.:|||||.
Human     1 MNPRKKVDLKLIIVGAIGVGKTSLLHQYVHKTFYEEYQTTLGASILSKIIILGDTTLKLQIWDTG 65

  Fly    66 GQERFQSLGVAFYRGADCCVLVYDVTAPNSFKNLDSWRDEFLIQASPRDPDHFPFVVLGNKVDLD 130
            |||||:|:...||:|:|.|:|.:|||...||:.||.||.:.|.:..|.: ..:|.|:||||:||.
Human    66 GQERFRSMVSTFYKGSDGCILAFDVTDLESFEALDIWRGDVLAKIVPME-QSYPMVLLGNKIDLA 129

  Fly   131 NRQVSTRRAQQWCQSKNDIPYYETSAKEGINVEMAFQVIAKNALE-----LEAE-AEVINDFPDQ 189
            :|:|....||.||:.| ||||:|.|||..|||..||:::|..||.     ||.. .|.|...|||
Human   130 DRKVPQEVAQGWCREK-DIPYFEVSAKNDINVVQAFEMLASRALSRYQSILENHLTESIKLSPDQ 193

  Fly   190  189
            Human   194  193

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rab7	NP_001247276.1	Rab7	9..179	CDD:206655	83/174 (48%)
		RAB	9..174	CDD:197555	79/164 (48%)
RAB7B	NP_001157994.1	Rab	9..169	CDD:206640	78/161 (48%)
		Effector region. /evidence=ECO:0000250	37..45		4/7 (57%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0394
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1172019at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR47981
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.920