DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rab7 and Rab5c

DIOPT Version :9

Sequence 1:	NP_001247276.1	Gene:	Rab7 / 42841	FlyBaseID:	FBgn0015795	Length:	207	Species:	Drosophila melanogaster
Sequence 2:	NP_001099310.2	Gene:	Rab5c / 287709	RGDID:	1307095	Length:	216	Species:	Rattus norvegicus

Alignment Length:	171	Identity:	69/171 - (40%)
Similarity:	101/171 - (59%)	Gaps:	6/171 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 SGRKKSLLKVIILGDSSVGKTSLMNQYVNKRFSNQYKATIGADFCTKEVVVNDRVVTMQIWDTAG 66
            :|.|....|:::||:|:|||:||:.::|..:|....::||||.|.|:.|.::|..|..:||||||
  Rat    15 AGNKICQFKLVLLGESAVGKSSLVLRFVKGQFHEYQESTIGAAFLTQTVCLDDTTVKFEIWDTAG 79

  Fly    67 QERFQSLGVAFYRGADCCVLVYDVTAPNSFKNLDSWRDEFLIQASPRDPDHFPFVVLGNKVDL-D 130
            |||:.||...:||||...::|||:|..::|....:|..|...||||    :....:.|||.|| .
  Rat    80 QERYHSLAPMYYRGAQAAIVVYDITNTDTFARAKNWVKELQRQASP----NIVIALAGNKADLAS 140

  Fly   131 NRQVSTRRAQQWCQSKNDIPYYETSAKEGINVEMAFQVIAK 171
            .|.|..:.||.:... |.:.:.|||||..:||...|..|||
  Rat   141 KRAVEFQEAQAYADD-NSLLFMETSAKTAMNVNEIFMAIAK 180

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rab7	NP_001247276.1	Rab7	9..179	CDD:206655	67/164 (41%)
Rab7	NP_001247276.1	RAB	9..174	CDD:197555	67/164 (41%)
Rab5c	NP_001099310.2	Rab5_related	21..183	CDD:206653	67/165 (41%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910