Protein Alignment Rab7 and RAB30

DIOPT Version :10

• Sequence 1: NP_524472.1
• Gene: Rab7 / 42841
• FlyBaseID: FBgn0015795
• Length: 207
• Species: Drosophila melanogaster
• Sequence 2: NP_055303.2
• Gene: RAB30 / 27314
• HGNCID: 9770
• Length: 203
• Species: Homo sapiens
• Alignment Length: 179
• Identity: 70/179 - (39%)
• Similarity: 109/179 - (60%)
• Gaps: 6/179 - (3%)

  Fly     8 LLKVIILGDSSVGKTSLMNQYVNKRFSNQYKATIGADFCTKEVVVNDRVVTMQIWDTAGQERFQS 72
            |.|::::|::.||||.|:.::....|.....||||.||..|.|.:|...|.:|||||||||||:|
Human     9 LFKIVLIGNAGVGKTCLVRRFTQGLFPPGQGATIGVDFMIKTVEINGEKVKLQIWDTAGQERFRS 73

  Fly    73 LGVAFYRGADCCVLVYDVTAPNSFKNLDSWRDEFLIQASPRDPDHFPFVVLGNKVDL-DNRQVST 136
            :..::||.|:..:|.||:|...||:.|..|..|....||    :....|::|||:|| :.|:||.
Human    74 ITQSYYRSANALILTYDITCEESFRCLPEWLREIEQYAS----NKVITVLVGNKIDLAERREVSQ 134

  Fly   137 RRAQQWCQSKNDIPYYETSAKEGINVEMAFQVIAKNALELEAEAEVIND 185
            :||:::.::: |:.|.||||||..|||..|..:|...:....:..::|:
Human   135 QRAEEFSEAQ-DMYYLETSAKESDNVEKLFLDLACRLISEARQNTLVNN 182

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rab7	NP_524472.1	Rab7	9..179	CDD:206655	68/170 (40%)
RAB30	NP_055303.2	Rab30	3..171	CDD:133314	69/166 (42%)
		Switch-I. /evidence=ECO:0000255|PROSITE-ProRule:PRU00753	36..44		3/7 (43%)
		Switch-II. /evidence=ECO:0000255|PROSITE-ProRule:PRU00753	67..83		8/15 (53%)