DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment Rab7 and rab-10

DIOPT Version :9

Sequence 1:NP_001247276.1 Gene:Rab7 / 42841 FlyBaseID:FBgn0015795 Length:207 Species:Drosophila melanogaster
Sequence 2:NP_491857.1 Gene:rab-10 / 266836 WormBaseID:WBGene00004273 Length:201 Species:Caenorhabditis elegans


Alignment Length:195 Identity:65/195 - (33%)
Similarity:109/195 - (55%) Gaps:15/195 - (7%)


- Green bases have known domain annotations that are detailed below.


  Fly     8 LLKVIILGDSSVGKTSLMNQYVNKRFSNQYKATIGADFCTKEVVVNDRVVTMQIWDTAGQERFQS 72
            |.|::::|||.||||.::.::.:..|:..:.:|||.||..|.:.:..:.:.:|||||||||||.:
 Worm     9 LFKLLLIGDSGVGKTCILYRFSDDAFNTTFISTIGIDFKIKTIELKGKKIKLQIWDTAGQERFHT 73

  Fly    73 LGVAFYRGADCCVLVYDVTAPNSFKNLDSWRDEFLIQASPRDPDHFPFVVLGNKVDLDNRQVSTR 137
            :..::||||...:||||:|...||.|:..|.......||    :....::||||.|:.:|:|.:|
 Worm    74 ITTSYYRGAMGIMLVYDITNAKSFDNIAKWLRNIDEHAS----EDVVKMILGNKCDMSDRRVVSR 134

  Fly   138 RAQQWCQSKNDIPYYETSAKEGINVEMAFQVIAKNALELEAEAEVINDFPDQITLGSQNNRPGNP 202
            ...:.....:.|.::|||||..::|:.||..:|:         .::...||  :...|:....||
 Worm   135 ERGEKIAQDHGISFHETSAKLNVHVDTAFYDLAE---------AILAKMPD--STDEQSRDTVNP 188

  Fly   203  202
             Worm   189  188

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Rab7NP_001247276.1 Rab7 9..179 CDD:206655 59/169 (35%)
RAB 9..174 CDD:197555 59/164 (36%)
rab-10NP_491857.1 Rab8_Rab10_Rab13_like 7..173 CDD:206659 60/176 (34%)
RAB 10..173 CDD:197555 59/175 (34%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

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