DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment Rab7 and Rab4a

DIOPT Version :9

Sequence 1:NP_001247276.1 Gene:Rab7 / 42841 FlyBaseID:FBgn0015795 Length:207 Species:Drosophila melanogaster
Sequence 2:NP_037151.2 Gene:Rab4a / 25532 RGDID:3529 Length:218 Species:Rattus norvegicus


Alignment Length:186 Identity:69/186 - (37%)
Similarity:112/186 - (60%) Gaps:12/186 - (6%)


- Green bases have known domain annotations that are detailed below.


  Fly     1 MSGRKKSLLKVIILGDSSVGKTSLMNQYVNKRFSNQYKATIGADFCTKEVVVNDRVVTMQIWDTA 65
            ||.....|.|.:::|::..||:.|::|::.|:|.:....|||.:|.:|.:.|..:.|.:||||||
  Rat     6 MSETYDFLFKFLVIGNAGTGKSCLLHQFIEKKFKDDSNHTIGVEFGSKIINVGGKYVKLQIWDTA 70

  Fly    66 GQERFQSLGVAFYRGADCCVLVYDVTAPNSFKNLDSWRDEFLIQASPRDPDHFPFVVLGNKVDLD 130
            |||||:|:..::||||...:||||:|:..::..|.:|..:..:.||    .:...::.|||.|||
  Rat    71 GQERFRSVTRSYYRGAAGALLVYDITSRETYNALTNWLTDARMLAS----QNIVIILCGNKKDLD 131

  Fly   131 -NRQVSTRRAQQWCQSKNDIPYYETSAKEGINVEMAFQVIAKNAL------ELEAE 179
             :|:|:...|.::.| :|::.:.||||..|.|||.||...|:..|      ||:.|
  Rat   132 ADREVTFLEASRFAQ-ENELMFLETSALTGENVEEAFMQCARKILNKIESGELDPE 186

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Rab7NP_001247276.1 Rab7 9..179 CDD:206655 65/176 (37%)
RAB 9..174 CDD:197555 62/165 (38%)
Rab4aNP_037151.2 Rab4 14..174 CDD:206696 62/164 (38%)
Effector region. /evidence=ECO:0000250 42..50 3/7 (43%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
21.910

Return to query results.
Submit another query.