DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rab7 and rho2

DIOPT Version :9

Sequence 1:	NP_001247276.1	Gene:	Rab7 / 42841	FlyBaseID:	FBgn0015795	Length:	207	Species:	Drosophila melanogaster
Sequence 2:	NP_594569.1	Gene:	rho2 / 2542773	PomBaseID:	SPAC16.01	Length:	200	Species:	Schizosaccharomyces pombe

Alignment Length:	179	Identity:	48/179 - (26%)
Similarity:	91/179 - (50%)	Gaps:	20/179 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 KVIILGDSSVGKTSLMNQYVNKRFSNQYKATIGADFCTKEVVVNDRVVTMQIWDTAGQERFQSLG 74
            |::::||.:.|||||::.:....|..:|..|:..:: ..:..|:.:.|.:.:|||||||.::.|.
pombe    10 KLVVVGDGACGKTSLLSVFTLGYFPTEYVPTVFENY-VSDCRVDGKSVQLALWDTAGQEEYERLR 73

  Fly    75 VAFYRGADCCVLVYDVTAPNSFKNLDS-WRDEFLIQASPRDPDHFPFVVLGNKVDLDNRQVS--- 135
            ...|..|...::.:.:.:|:|.:|:.: |.:| :....|    :.||:::|.|.||.:..|:
pombe    74 PMSYAKAHIILVGFAIDSPDSLENVSTKWIEE-INTLCP----NVPFILVGMKADLRSDPVAIEE 133

  Fly   136 -TRRAQQWCQSK---------NDIPYYETSAKEGINVEMAFQVIAKNAL 174
             .||.|.:.:|:         ....|.|.|:..|..|:..|:...:.||
pombe   134 MRRRNQNFVKSQQAELVAQRIGARKYMECSSLTGDGVDDVFEAATRAAL 182

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rab7	NP_001247276.1	Rab7	9..179	CDD:206655	48/179 (27%)
Rab7	NP_001247276.1	RAB	9..174	CDD:197555	46/177 (26%)
rho2	NP_594569.1	Rho2	8..199	CDD:206702	48/179 (27%)
rho2	NP_594569.1	RHO	11..183	CDD:197554	47/178 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910