DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rab7 and ypt4

DIOPT Version :9

Sequence 1:	NP_001247276.1	Gene:	Rab7 / 42841	FlyBaseID:	FBgn0015795	Length:	207	Species:	Drosophila melanogaster
Sequence 2:	NP_594796.1	Gene:	ypt4 / 2542113	PomBaseID:	SPAC1B3.11c	Length:	234	Species:	Schizosaccharomyces pombe

Alignment Length:	207	Identity:	75/207 - (36%)
Similarity:	113/207 - (54%)	Gaps:	17/207 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 LLKVIILGDSSVGKTSLMNQYVNKRFSNQYKATIGADFCTKEVVV----NDRVVTMQIWDTAGQE 68
            |:|:::.|.|..||:.|:.::|..::.:|...|:|.||.::.:.|    ..:.:.:|||||||||
pombe     9 LVKIVLAGPSGTGKSCLLQRFVKNQWDDQVSHTVGIDFASRIISVGMGNQQKRIKLQIWDTAGQE 73

  Fly    69 RFQSLGVAFYRGADCCVLVYDVTAPNSFKNLDSWRDEFLIQASPRDPDHFPFVVLGNKVDLDN-R 132
            :|:|:...:||||...|||||||..:||:.|.||..:....|    |.....|:.|:|.||.| |
pombe    74 KFRSVARNYYRGAAGAVLVYDVTNKDSFEELSSWLSDIRAMA----PSTICVVLAGSKSDLQNQR 134

  Fly   133 QVSTRRAQQWCQSKNDIPYYETSAKEGINVEMAFQVIAKNALELEAEAEVINDFPDQITLGSQN- 196
            ||||..|.::|..|:....:|||:..|.|||..|..:....:......|:  |..|| :||.|.
pombe   135 QVSTEEAAEFCSEKHISSAHETSSYTGSNVEECFLSVVSTIITRIELGEI--DPQDQ-SLGIQYG 196

  Fly   197 ----NRPGNPDN 204
                .||.:|.:
pombe   197 DLSFRRPVHPSS 208

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rab7	NP_001247276.1	Rab7	9..179	CDD:206655	64/174 (37%)
Rab7	NP_001247276.1	RAB	9..174	CDD:197555	64/169 (38%)
ypt4	NP_594796.1	RAB	10..178	CDD:197555	64/171 (37%)
ypt4	NP_594796.1	Rab	10..173	CDD:206640	64/166 (39%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910