DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rab7 and rho1

DIOPT Version :9

Sequence 1:	NP_001247276.1	Gene:	Rab7 / 42841	FlyBaseID:	FBgn0015795	Length:	207	Species:	Drosophila melanogaster
Sequence 2:	NP_594490.1	Gene:	rho1 / 2541612	PomBaseID:	SPAC1F7.04	Length:	202	Species:	Schizosaccharomyces pombe

Alignment Length:	183	Identity:	50/183 - (27%)
Similarity:	79/183 - (43%)	Gaps:	28/183 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 KVIILGDSSVGKTSLMNQYVNKRFSNQYKATIGADFCTKEVVVNDRVVTMQIWDTAGQERFQSLG 74
            |::|:||.:.|||.|:..:....|...|..|:..:: ..:|.|:.|.|.:.:|||||||.:..|.
pombe     8 KLVIVGDGACGKTCLLIVFSKGTFPEVYVPTVFENY-VADVEVDGRHVELALWDTAGQEDYDRLR 71

  Fly    75 VAFYRGADCCVLVYDVTAPNSFKNL-DSWRDEFLIQASPRDPDHF----PFVVLGNKVDLDN--- 131
            ...|..:...::.:.|.:|:|..|: :.|..|.|         ||    |.:::..|.||.|
pombe    72 PLSYPDSHVILICFAVDSPDSLDNVQEKWISEVL---------HFCSSLPILLVACKADLRNDPK 127

  Fly   132 ----------RQVSTRRAQQWCQSKNDIPYYETSAKEGINVEMAFQVIAKNAL 174
                      ..|:|...|...|......|.|.|||....|...|:...:.|:
pombe   128 IIEELSKTNQHPVTTEEGQAVAQKIGAYKYLECSAKTNEGVREVFESATRAAM 180

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rab7	NP_001247276.1	Rab7	9..179	CDD:206655	50/183 (27%)
Rab7	NP_001247276.1	RAB	9..174	CDD:197555	49/181 (27%)
rho1	NP_594490.1	RhoA_like	6..180	CDD:206662	49/181 (27%)
rho1	NP_594490.1	RHO	9..182	CDD:197554	49/182 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910