DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rab7 and RAB38

DIOPT Version :9

Sequence 1:	NP_001247276.1	Gene:	Rab7 / 42841	FlyBaseID:	FBgn0015795	Length:	207	Species:	Drosophila melanogaster
Sequence 2:	NP_071732.1	Gene:	RAB38 / 23682	HGNCID:	9776	Length:	211	Species:	Homo sapiens

Alignment Length:	183	Identity:	66/183 - (36%)
Similarity:	110/183 - (60%)	Gaps:	13/183 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 KKSLLKVIILGDSSVGKTSLMNQYVNKRFSNQYKATIGADFCTKEVVVN---DRVVTMQIWDTAG 66
            |:.|.|::::||..|||||::.:||::.||:.|:||||.||..|  |::   :.||.:|:||.||
Human     6 KEHLYKLLVIGDLGVGKTSIIKRYVHQNFSSHYRATIGVDFALK--VLHWDPETVVRLQLWDIAG 68

  Fly    67 QERFQSLGVAFYRGADCCVLVYDVTAPNSFKNLDSWRDEFLIQASPRDPDHFPFVVLGNKVD--- 128
            ||||.::...:||.|....:|:|||.|.:|:.:..|:::...:.|..:......|:|.||.|
Human    69 QERFGNMTRVYYREAMGAFIVFDVTRPATFEAVAKWKNDLDSKLSLPNGKPVSVVLLANKCDQGK 133

  Fly   129 --LDNRQVSTRRAQQWCQSKNDIPYYETSAKEGINVEMAFQVIAKNALELEAE 179
              |.|..:   :..|:|:....:.::||||||.||::.|.:.:.|:.|..|.:
Human   134 DVLMNNGL---KMDQFCKEHGFVGWFETSAKENINIDEASRCLVKHILANECD 183

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rab7	NP_001247276.1	Rab7	9..179	CDD:206655	64/177 (36%)
Rab7	NP_001247276.1	RAB	9..174	CDD:197555	62/172 (36%)
RAB38	NP_071732.1	Rab32_Rab38	10..208	CDD:206692	64/179 (36%)
RAB38	NP_071732.1	Effector region. /evidence=ECO:0000250	38..46		5/7 (71%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910