DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rab7 and Rasl2-9

DIOPT Version :9

Sequence 1:	NP_001247276.1	Gene:	Rab7 / 42841	FlyBaseID:	FBgn0015795	Length:	207	Species:	Drosophila melanogaster
Sequence 2:	NP_033054.1	Gene:	Rasl2-9 / 19428	MGIID:	104605	Length:	216	Species:	Mus musculus

Alignment Length:	193	Identity:	58/193 - (30%)
Similarity:	98/193 - (50%)	Gaps:	17/193 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 GRKKSLLKVIILGDSSVGKTSLMNQYVNKRFSNQYKATIGADFCTKEVVVNDRVVTMQIWDTAGQ 67
            |..:...||:::||...|||:.|.:::...|..:|.||:|.:..|.....|...:...:||||||
Mouse     5 GEPQVQFKVVLVGDGGTGKTTFMKRHLTGEFEKEYVATLGVEVHTLVFHTNRGPIKFNVWDTAGQ 69

  Fly    68 ERFQSLGVAFYRGADCCVLVYDVTAPNSFKNLDSWRDEFLIQASPRDPDHFPFVVLGNKVDLDNR 132
            |:|..|...:|..|.|.::::|||:..::||:.||..:.:     |..::.|.|:.|||||:.:.
Mouse    70 EKFGGLRDGYYIQAQCAIIMFDVTSRVTYKNVPSWHKDLV-----RVCENIPIVLCGNKVDVKDM 129

  Fly   133 QVSTRRAQQWCQSKNDIPYYETSAKEGINVEMAFQVIAKN----------ALELEAEAEVIND 185
            :|..:..  ....|.::.||:.||:...|.|..|..:|:.          |:...|..||:.|
Mouse   130 KVKAKPI--LFHRKKNLQYYDISARSNYNFEKPFFWLARKLIGDPNLEFVAMPALAPPEVVMD 190

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rab7	NP_001247276.1	Rab7	9..179	CDD:206655	53/179 (30%)
Rab7	NP_001247276.1	RAB	9..174	CDD:197555	52/174 (30%)
Rasl2-9	NP_033054.1	Ran	11..176	CDD:206643	52/171 (30%)
Rasl2-9	NP_033054.1	RAN	16..215	CDD:128473	55/182 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910