Protein Alignment Rab7 and Rab4a

DIOPT Version :10

• Sequence 1: NP_524472.1
• Gene: Rab7 / 42841
• FlyBaseID: FBgn0015795
• Length: 207
• Species: Drosophila melanogaster
• Sequence 2: NP_033029.2
• Gene: Rab4a / 19341
• MGIID: 105069
• Length: 218
• Species: Mus musculus
• Alignment Length: 186
• Identity: 69/186 - (37%)
• Similarity: 112/186 - (60%)
• Gaps: 12/186 - (6%)

  Fly     1 MSGRKKSLLKVIILGDSSVGKTSLMNQYVNKRFSNQYKATIGADFCTKEVVVNDRVVTMQIWDTA 65
            ||.....|.|.:::|::..||:.|::|::.|:|.:....|||.:|.:|.:.|..:.|.:||||||
Mouse     6 MSETYDFLFKFLVIGNAGTGKSCLLHQFIEKKFKDDSNHTIGVEFGSKIINVGGKYVKLQIWDTA 70

  Fly    66 GQERFQSLGVAFYRGADCCVLVYDVTAPNSFKNLDSWRDEFLIQASPRDPDHFPFVVLGNKVDLD 130
            |||||:|:..::||||...:||||:|:..::..|.:|..:..:.||    .:...::.|||.|||
Mouse    71 GQERFRSVTRSYYRGAAGALLVYDITSRETYNALTNWLTDARMLAS----QNIVLILCGNKKDLD 131

  Fly   131 -NRQVSTRRAQQWCQSKNDIPYYETSAKEGINVEMAFQVIAKNAL------ELEAE 179
             :|:|:...|.::.| :|::.:.||||..|.|||.||...|:..|      ||:.|
Mouse   132 ADREVTFLEASRFAQ-ENELMFLETSALTGENVEEAFMQCARKILNKIESGELDPE 186

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rab7	NP_524472.1	Rab7	9..179	CDD:206655	65/176 (37%)
Rab4a	NP_033029.2	Rab4	14..174	CDD:206696	62/164 (38%)
		Switch 1. /evidence=ECO:0000250|UniProtKB:P61106	44..49		3/4 (75%)
		Switch 2. /evidence=ECO:0000250|UniProtKB:P61106	70..79		7/8 (88%)