DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rab7 and Rab23

DIOPT Version :9

Sequence 1:	NP_001247276.1	Gene:	Rab7 / 42841	FlyBaseID:	FBgn0015795	Length:	207	Species:	Drosophila melanogaster
Sequence 2:	NP_001153201.1	Gene:	Rab23 / 19335	MGIID:	99833	Length:	237	Species:	Mus musculus

Alignment Length:	193	Identity:	65/193 - (33%)
Similarity:	114/193 - (59%)	Gaps:	11/193 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 LKVIILGDSSVGKTSLMNQYVNKRFSNQYKATIGADFCTKEVVVNDRVVTMQIWDTAGQERFQSL 73
            :|::::|:.:|||:|::.:|....|:..||.|||.||..:::.|||..|.:.:|||||||.|.::
Mouse    10 IKMVVVGNGAVGKSSMIQRYCKGIFTKDYKKTIGVDFLERQIQVNDEDVRLMLWDTAGQEEFDAI 74

  Fly    74 GVAFYRGADCCVLVYDVTAPNSFKNLDSWRDEFLIQASPRDPDHFPFVVLGNKVD-LDNRQVSTR 137
            ..|:||||..||||:..|...||:.:.|||::.:.:..     ..|..::.||:| ||:..:...
Mouse    75 TKAYYRGAQACVLVFSTTDRESFEAISSWREKVVAEVG-----DIPTALVQNKIDLLDDSCIKNE 134

  Fly   138 RAQQWCQSKNDIPYYETSAKEGINVEMAFQVIAKNALELEAEAEVINDFPDQITLGSQNNRPG 200
            .|:...: :..:.:|.||.||.:||...|:.:|:..|: :.:.::..| |:|  ..|.:|:.|
Mouse   135 EAEGLAK-RLKLRFYRTSVKEDLNVSEVFKYLAEKHLQ-KLKQQITED-PEQ--THSSSNKIG 192

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rab7	NP_001247276.1	Rab7	9..179	CDD:206655	59/170 (35%)
Rab7	NP_001247276.1	RAB	9..174	CDD:197555	58/165 (35%)
Rab23	NP_001153201.1	Rab23_like	10..169	CDD:133306	58/164 (35%)
		Effector region. /evidence=ECO:0000250	38..46		5/7 (71%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	204..237
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910