DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rab7 and rab-28

DIOPT Version :9

Sequence 1:	NP_001247276.1	Gene:	Rab7 / 42841	FlyBaseID:	FBgn0015795	Length:	207	Species:	Drosophila melanogaster
Sequence 2:	NP_501609.1	Gene:	rab-28 / 189429	WormBaseID:	WBGene00004281	Length:	248	Species:	Caenorhabditis elegans

Alignment Length:	206	Identity:	60/206 - (29%)
Similarity:	107/206 - (51%)	Gaps:	21/206 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 LLKVIILGDSSVGKTSLMNQYVNKRFSNQYKATIGADFCTKEVVV-NDRVVTMQIWDTAGQERFQ 71
            ::|::::||.:.||||:..::..:.|...|..|:|.||.::.:.: ::..|.:|:||..||....
Worm    35 VIKIVVVGDGASGKTSICQRFAKESFDKSYHQTLGLDFFSRRITLPHEMQVLVQVWDIGGQSIAG 99

  Fly    72 SLGVAFYRGADCCVLVYDVTAPNSFKNLDSWRDEFLIQASPRDPD-HFPFVVLGNKVDLDNRQVS 135
            .:...:..||:...||||||...||:|...|..  :::.:.:..: ....|::|||.||:.|:|.
Worm   100 EMIDKYLTGANIVFLVYDVTNSKSFENAVDWLS--VVKKNTKSSETPVKLVLMGNKTDLEERRVV 162

  Fly   136 TRRAQQWCQSKND-IPYYETSAKEGINVEMAF-QVIAK------NALELEAEAEVINDFPDQITL 192
            :..|.:...:.|| :|.| .|||.|..|.:.| |.:|:      :..|:||:.|::.
Worm   163 SVEAHKNFATSNDMMPTY-VSAKTGDTVFLTFRQAVAEVLNVGLSRAEVEADIEIVQ-------- 218

  Fly   193 GSQNNRPGNPD 203
            ||...:|...|
Worm   219 GSVIEQPKQSD 229

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rab7	NP_001247276.1	Rab7	9..179	CDD:206655	54/179 (30%)
Rab7	NP_001247276.1	RAB	9..174	CDD:197555	52/174 (30%)
rab-28	NP_501609.1	Rab28	36..248	CDD:206694	60/205 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910