DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment Rab7 and rab-21

DIOPT Version :9

Sequence 1:NP_001247276.1 Gene:Rab7 / 42841 FlyBaseID:FBgn0015795 Length:207 Species:Drosophila melanogaster
Sequence 2:NP_495854.1 Gene:rab-21 / 187932 WormBaseID:WBGene00004279 Length:207 Species:Caenorhabditis elegans


Alignment Length:173 Identity:58/173 - (33%)
Similarity:107/173 - (61%) Gaps:6/173 - (3%)


- Green bases have known domain annotations that are detailed below.


  Fly     4 RKKSLLKVIILGDSSVGKTSLMNQYVNKRFSNQYKATIGADFCTKEVVVNDRVVTMQIWDTAGQE 68
            :|....|:::||:..|||:||:.::|..:||.::.:||.|.|..|.|.|.|....:.||||||||
 Worm     8 QKSFKFKIVLLGEGCVGKSSLVLRFVENKFSCKHLSTIQASFQNKTVNVEDCQADLHIWDTAGQE 72

  Fly    69 RFQSLGVAFYRGADCCVLVYDVTAPNSFKNLDSWRDEFLIQASPRDPDHFPFVVLGNKVDL-DNR 132
            ::.:||..:|||::..:||:|:|...||:.:.:|    :::......:....:::|||:|| :.|
 Worm    73 KYHALGPIYYRGSNGVLLVFDITDRKSFEKVKNW----VLEIKTCLGNTAEILIVGNKIDLEEER 133

  Fly   133 QVSTRRAQQWCQSKNDIPYYETSAKEGINVEMAFQVIAKNALE 175
            ||:.:.|:.:.:|:..: |.||||::.:.:..||:.:....:|
 Worm   134 QVTRQDAEAYAESEGAL-YMETSAQDNVGISDAFESLTAKMIE 175

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Rab7NP_001247276.1 Rab7 9..179 CDD:206655 57/168 (34%)
RAB 9..174 CDD:197555 56/165 (34%)
rab-21NP_495854.1 Rab21 13..174 CDD:133323 56/165 (34%)
Ras 14..175 CDD:278499 56/165 (34%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
21.910

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