DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rab7 and rap-1

DIOPT Version :9

Sequence 1:	NP_001247276.1	Gene:	Rab7 / 42841	FlyBaseID:	FBgn0015795	Length:	207	Species:	Drosophila melanogaster
Sequence 2:	NP_501549.1	Gene:	rap-1 / 177709	WormBaseID:	WBGene00004307	Length:	188	Species:	Caenorhabditis elegans

Alignment Length:	198	Identity:	59/198 - (29%)
Similarity:	99/198 - (50%)	Gaps:	17/198 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 KVIILGDSSVGKTSLMNQYVNKRFSNQYKATIGADFCTKEVVVNDRVVTMQIWDTAGQERFQSLG 74
            |:::||...|||::|..|:|...|..:|..|| .|...|:|.|:.:...::|.||||.|:|.::.
Worm     5 KIVVLGSGGVGKSALTVQFVQGIFVEKYDPTI-EDSYRKQVEVDGQQCMLEILDTAGTEQFTAMR 68

  Fly    75 VAFYRGADCCVLVYDVTAPNSFKNLDSWRDEFLIQASPRDPDHFPFVVLGNKVDLDNRQVSTRRA 139
            ..:.:.....||||.:||.::|.:|...||:.|   ..:|.|..|.:::|||.||::.:|..:..
Worm    69 DLYMKNGQGFVLVYSITAQSTFNDLMDLRDQIL---RVKDTDEVPMILVGNKCDLEDERVVGKDQ 130

  Fly   140 QQWCQSKNDIPYYETSAKEGINVEMAFQVIAKNALELEAEAEVINDFPDQITLGSQNNRPGNPDN 204
            .|....:....:.|||||..|||...|..:.:         ::...:|:......|:|:    ..
Worm   131 GQNLARQFGSAFLETSAKAKINVSEVFYDLVR---------QINRRYPESGRRQGQSNK----QC 182

  Fly   205 CQC 207
            |.|
Worm   183 CSC 185

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rab7	NP_001247276.1	Rab7	9..179	CDD:206655	54/168 (32%)
Rab7	NP_001247276.1	RAB	9..174	CDD:197555	54/163 (33%)
rap-1	NP_501549.1	Rap1	3..166	CDD:133375	54/173 (31%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910