DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rab7 and rab-7

DIOPT Version :9

Sequence 1:	NP_001247276.1	Gene:	Rab7 / 42841	FlyBaseID:	FBgn0015795	Length:	207	Species:	Drosophila melanogaster
Sequence 2:	NP_496549.1	Gene:	rab-7 / 174834	WormBaseID:	WBGene00004271	Length:	209	Species:	Caenorhabditis elegans

Alignment Length:	209	Identity:	151/209 - (72%)
Similarity:	175/209 - (83%)	Gaps:	4/209 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MSG-RKKSLLKVIILGDSSVGKTSLMNQYVNKRFSNQYKATIGADFCTKEVVVNDRVVTMQIWDT 64
            ||| |||:||||||||||.||||||||||||:||||||||||||||.|::|.::||.||:|||||
Worm     1 MSGTRKKALLKVIILGDSGVGKTSLMNQYVNRRFSNQYKATIGADFLTRDVNIDDRTVTLQIWDT 65

  Fly    65 AGQERFQSLGVAFYRGADCCVLVYDVTAPNSFKNLDSWRDEFLIQASPRDPDHFPFVVLGNKVDL 129
            ||||||||||||||||||||||.:|||...|||:|||||||||||||||||||||||:|||||||
Worm    66 AGQERFQSLGVAFYRGADCCVLAFDVTNAASFKSLDSWRDEFLIQASPRDPDHFPFVLLGNKVDL 130

  Fly   130 DN-RQVSTRRAQQWCQSKNDIPYYETSAKEGINVEMAFQVIAKNALELEA-EAEVINDFPDQITL 192
            :: |.||::|||.|||:|.:|||||.||||.:|||.||..||::||..|: |.....:|||||.|
Worm   131 ESQRAVSSKRAQSWCQTKGNIPYYEVSAKEALNVEAAFLAIARDALARESQETNDFPEFPDQIRL 195

  Fly   193 G-SQNNRPGNPDNC 205
            . :|.|:..:..||
Worm   196 NPNQQNQQNSGCNC 209

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rab7	NP_001247276.1	Rab7	9..179	CDD:206655	133/171 (78%)
Rab7	NP_001247276.1	RAB	9..174	CDD:197555	130/165 (79%)
rab-7	NP_496549.1	Rab7	10..181	CDD:206655	133/170 (78%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	271	1.000	Domainoid score	I953
eggNOG	1	0.900	-	-		E1_KOG0394
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H100564
Inparanoid	1	1.050	296	1.000	Inparanoid score	I1661
Isobase	1	0.950	-	0	Normalized mean entropy	S534
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1172019at2759
OrthoFinder	1	1.000	-	-		FOG0001661
OrthoInspector	1	1.000	-	-		oto18489
orthoMCL	1	0.900	-	-		OOG6_101358
Panther	1	1.100	-	-	LDO	PTHR47981
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2001
SonicParanoid	1	1.000	-	-		X1058
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	14	13.850