Protein Alignment Rab7 and DIRAS1

DIOPT Version :9

• Sequence 1: NP_001247276.1
• Gene: Rab7 / 42841
• FlyBaseID: FBgn0015795
• Length: 207
• Species: Drosophila melanogaster
• Sequence 2: XP_011526015.1
• Gene: DIRAS1 / 148252
• HGNCID: 19127
• Length: 232
• Species: Homo sapiens
• Alignment Length: 182
• Identity: 59/182 - (32%)
• Similarity: 91/182 - (50%)
• Gaps: 36/182 - (19%)

  Fly    10 KVIILGDSSVGKTSLMNQYVNKRFSNQYKATIGADFCTKEVVVNDR-VVTMQIWDTAGQERFQSL 73
            :|::.|...|||:||:.::|...|.:.|..||...:  ::|:..|: |.|:||.||.|..:|.::
Human    43 RVVVFGAGGVGKSSLVLRFVKGTFRDTYIPTIEDTY--RQVISCDKSVCTLQITDTTGSHQFPAM 105

  Fly    74 -------GVAFYRGADCCVLVYDVTAPNSFKNLDS-WRDEFLIQASPRDPDHFPFVVLGNKVDLD 130
                   |.||       :||:.||:..|.:.|.. ::....|:.|..|   .|.:::|||.|..
Human   106 QRLSISKGHAF-------ILVFSVTSKQSLEELGPIYKLIVQIKGSVED---IPVMLVGNKCDET 160

  Fly   131 NRQVSTRR----AQQW-CQSKNDIPYYETSAKEGINVEMAFQVIAKNALELE 177
            .|:|.||.    ||:| |      .:.|||||...||:..||.:    |.||
Human   161 QREVDTREAQAVAQEWKC------AFMETSAKMNYNVKELFQEL----LTLE 202

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rab7	NP_001247276.1	Rab7	9..179	CDD:206655	59/182 (32%)
		RAB	9..174	CDD:197555	56/177 (32%)
DIRAS1	XP_011526015.1	PTZ00369	39..232	CDD:240385	59/182 (32%)
		P-loop_NTPase	41..202	CDD:304359	57/180 (32%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910