DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rab7 and AgaP_AGAP005248

DIOPT Version :9

Sequence 1:	NP_001247276.1	Gene:	Rab7 / 42841	FlyBaseID:	FBgn0015795	Length:	207	Species:	Drosophila melanogaster
Sequence 2:	XP_314163.4	Gene:	AgaP_AGAP005248 / 1274961	VectorBaseID:	AGAP005248	Length:	280	Species:	Anopheles gambiae

Alignment Length:	180	Identity:	48/180 - (26%)
Similarity:	89/180 - (49%)	Gaps:	10/180 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 LKVIILGDSSVGKTSLMNQYVNKRFSNQYKATIGADFCTKEVVVNDRVVTMQIWDTAGQERFQSL 73
            ::::|||.:.|||:.::.:::.|.:|::|:.|: .|...:|..:....:.:.|.||:|:.:|.::
Mosquito     7 IRLVILGGAGVGKSCIIKRFLFKTYSDKYRPTV-EDLYNREYDLGSVTLKVDILDTSGEMQFPAM 70

  Fly    74 GVAFYRGADCCVLVYDVTAPNSFKNLDSWRDEFLIQASPRDPDHFPFVVLGNKVDL--DNRQVST 136
            .......|...:|||..|:..|...:....:|  |:....|....|.|::|||.||  .:|:|..
Mosquito    71 RRLSIATAHAFLLVYATTSEASLGCVKQCFEE--IREQRADFQDIPMVIVGNKYDLTASHREVRI 133

  Fly   137 RRAQQW--CQ-SKNDIPYYETSAKEGINVEMAFQ--VIAKNALELEAEAE 181
            ....:|  |: .|..:...|.|||:..|:...|:  |.....|.:...||
Mosquito   134 EDVSEWVFCELPKLKVKVLECSAKDDYNIMEIFRTFVTLSRILPVNGSAE 183

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rab7	NP_001247276.1	Rab7	9..179	CDD:206655	46/176 (26%)
Rab7	NP_001247276.1	RAB	9..174	CDD:197555	45/171 (26%)
AgaP_AGAP005248	XP_314163.4	Ras	8..172	CDD:206642	45/166 (27%)
AgaP_AGAP005248	XP_314163.4	small_GTPase	8..170	CDD:197466	44/164 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910