DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rab7 and cracr2aa

DIOPT Version :9

Sequence 1:	NP_001247276.1	Gene:	Rab7 / 42841	FlyBaseID:	FBgn0015795	Length:	207	Species:	Drosophila melanogaster
Sequence 2:	XP_002667614.5	Gene:	cracr2aa / 100330395	ZFINID:	ZDB-GENE-110427-1	Length:	718	Species:	Danio rerio

Alignment Length:	155	Identity:	56/155 - (36%)
Similarity:	90/155 - (58%)	Gaps:	4/155 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 LLKVIILGDSSVGKTSLMNQYVNKRFSNQYKATIGADFCTKEVVVNDRVVTMQIWDTAGQERFQS 72
            |.||:::|:||||||||:.::.:..|.:...||:|.|:..|.:.|::..:.:|:||||||||::|
Zfish   532 LFKVVLVGNSSVGKTSLLRRFCDDCFHSGTCATVGIDYSVKTLSVDNSQIALQMWDTAGQERYRS 596

  Fly    73 LGVAFYRGADCCVLVYDVTAPNSFKNLDSWRDEFLIQASPRDPDHFPFVVLGNKVDLDNRQVSTR 137
            :...|:|.||..|:|||:|...:|..:..|    |........:..|.::||||.|||:::|...
Zfish   597 ITKQFFRKADGVVVVYDITNEQTFTAVRQW----LASVQEGAGEDIPIMLLGNKTDLDSQRVIPL 657

  Fly   138 RAQQWCQSKNDIPYYETSAKEGINV 162
            ...:.......:.:||.||....||
Zfish   658 GLGEKLAKDFQLMFYECSAFSNHNV 682

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rab7	NP_001247276.1	Rab7	9..179	CDD:206655	55/154 (36%)
Rab7	NP_001247276.1	RAB	9..174	CDD:197555	55/154 (36%)
cracr2aa	XP_002667614.5	EF-hand_7	35..97	CDD:316058
		SMC_N	<162..>371	CDD:330553
		Rab	533..691	CDD:206640	55/154 (36%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.910