DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rab7 and rab6b

DIOPT Version :9

Sequence 1:	NP_001247276.1	Gene:	Rab7 / 42841	FlyBaseID:	FBgn0015795	Length:	207	Species:	Drosophila melanogaster
Sequence 2:	NP_001090835.1	Gene:	rab6b / 100038231	XenbaseID:	XB-GENE-493829	Length:	208	Species:	Xenopus tropicalis

Alignment Length:	203	Identity:	77/203 - (37%)
Similarity:	113/203 - (55%)	Gaps:	14/203 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 KVIILGDSSVGKTSLMNQYVNKRFSNQYKATIGADFCTKEVVVNDRVVTMQIWDTAGQERFQSLG 74
            |::.||:.|||||||:.:::...|.|.|:||||.||.:|.:.:.||.|.:|:|||||||||:||.
Frog    15 KLVFLGEQSVGKTSLITRFMYDSFDNTYQATIGIDFLSKTMYLEDRTVRLQLWDTAGQERFRSLI 79

  Fly    75 VAFYRGADCCVLVYDVTAPNSFKNLDSWRDEFLIQASPRDPDHFPFVVLGNKVDL-DNRQVSTRR 138
            .::.|.:...|:|||:|..|||.....|.|:.   .:.|..|.. .:::|||.|| |.||::...
Frog    80 PSYIRDSTVAVVVYDITNLNSFHQTSKWIDDV---RTERGSDVI-IMLVGNKTDLADKRQITIEA 140

  Fly   139 AQQWCQSKNDIPYYETSAKEGINVEMAFQVIAKNALELEAEAEVINDFPDQITLGSQNNRPGNPD 203
            .:|..:..| :.:.|||||.|.||:..|:.:|.....:|...|...|....|.|    ::|..|.
Frog   141 GEQKAKELN-VMFIETSAKTGYNVKQLFRRVASALPGMECSEEKSKDGMIDIKL----DKPQEPQ 200

  Fly   204 ----NCQC 207
                .|.|
Frog   201 VADAGCSC 208

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rab7	NP_001247276.1	Rab7	9..179	CDD:206655	69/169 (41%)
Rab7	NP_001247276.1	RAB	9..174	CDD:197555	68/164 (41%)
rab6b	NP_001090835.1	Rab6	14..174	CDD:206654	68/163 (42%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910