DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rab7 and rab9b

DIOPT Version :9

Sequence 1:	NP_001247276.1	Gene:	Rab7 / 42841	FlyBaseID:	FBgn0015795	Length:	207	Species:	Drosophila melanogaster
Sequence 2:	XP_001339262.1	Gene:	rab9b / 100003363	ZFINID:	ZDB-GENE-091118-112	Length:	202	Species:	Danio rerio

Alignment Length:	201	Identity:	99/201 - (49%)
Similarity:	128/201 - (63%)	Gaps:	8/201 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MSGRKKSLLKVIILGDSSVGKTSLMNQYVNKRFSNQYKATIGADFCTKEVVVNDRVVTMQIWDTA 65
            ||| |..|||||:|||..|||:||||:||..||.:|...|||.:|..:::.::.|:||:||||||
Zfish     1 MSG-KSLLLKVILLGDGGVGKSSLMNRYVTDRFDSQSFHTIGVEFLNRDLEIDGRLVTLQIWDTA 64

  Fly    66 GQERFQSLGVAFYRGADCCVLVYDVTAPNSFKNLDSWRDEFLIQASPRDPDHFPFVVLGNKVDLD 130
            |||||:||...||||||||:|.:.|....||:||..|:.||:..:..|||:.|||||||||||.:
Zfish    65 GQERFKSLRTPFYRGADCCLLTFAVDDLQSFQNLGCWKKEFMYYSDVRDPERFPFVVLGNKVDKE 129

  Fly   131 NRQVSTRRAQQWCQSKNDIPYYETSAKEGINVEMAFQVIAKNALELEAEAEVINDFPDQITLGSQ 195
            .|:|....|:.||:.....||:|||||:..||..||:...:..|..|       |..|...|.|.
Zfish   130 EREVGEDEARAWCEENGCCPYFETSAKDDTNVGAAFEAAVREVLASE-------DPIDHTLLSSS 187

  Fly   196 NNRPGN 201
            .:..||
Zfish   188 IDLHGN 193

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rab7	NP_001247276.1	Rab7	9..179	CDD:206655	88/169 (52%)
Rab7	NP_001247276.1	RAB	9..174	CDD:197555	86/164 (52%)
rab9b	XP_001339262.1	Rab9	3..172	CDD:206697	89/169 (53%)
rab9b	XP_001339262.1	RAB	8..174	CDD:197555	86/165 (52%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1172019at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.920