DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG13604 and YLR345W

DIOPT Version :9

Sequence 1:	NP_001262894.1	Gene:	CG13604 / 42840	FlyBaseID:	FBgn0039137	Length:	763	Species:	Drosophila melanogaster
Sequence 2:	NP_013449.1	Gene:	YLR345W / 851059	SGDID:	S000004337	Length:	509	Species:	Saccharomyces cerevisiae

Alignment Length:	430	Identity:	88/430 - (20%)
Similarity:	155/430 - (36%)	Gaps:	135/430 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly   383 PDIIEGSSFEESEQSVEKYLRQTLKPCL--------ELPSVQLLNSHNLTHQHNPNTPTIEITTN 439
            |...||.:|      |||...|.|...|        :|.....||...:..: |..|...||...
Yeast   138 PTSKEGVAF------VEKLRMQMLNDILAFFNDLSGQLAIYDALNIRKIDRK-NLETTFSEIGVK 195

  Fly   440 MSSSSTSMSKQPVDEILVEPPAAQPPRPDDTLSVHSDHSLHPGSLDASHAKNRKIY-IMRHGERV 503
            :....:.:|    |:.::....|.....:|...:.:|.::.......|  .|...| :|.|.|.:
Yeast   196 VLFIESIVS----DQEIMNRNIALALESNDYKGLSTDEAIDEYMRRLS--VNEPYYEMMTHDEEL 254

  Fly   504 DF----TFGTWIPYCFDEFGNYMRKDLNMPKTLPRRK----------NSPEGWQNDSPLTNVGVY 554
            .:    ..|..|....:..|..:.|.:.....|.::|          :..:.:.:|..|...|::
Yeast   255 SYIKYINLGKQIIVKDNIHGYLVNKIVFFLMNLRQKKGCVYFARCGTSDKDNYIHDEELNEEGIH 319

  Fly   555 QANLIGQALLEAQVQ--------------ID--H---------VYCSPSYRCIQTCTSAL----E 590
            .:.::...:|:...|              ||  |         |:..|..|   |..:||    |
Yeast   320 YSQVLKDFVLQRIKQKRQAKKNSDSLVEVIDGSHDEDLKTSLIVWTGPRKR---THDTALFFSKE 381

  Fly   591 GLKLTGKQKIK-LEPGLFEWMAWYPSGVPDWLTKNELTEAKFDVDLDYEPVQPASELTARLKEST 654
            |:|:..:.::: |.||          .:.| ||..::.: ||               .:..|||.
Yeast   382 GIKVQQRSELRQLNPG----------SIAD-LTDQQIMD-KF---------------PSEYKESL 419

  Fly   655 EQFY-------ERNHDVILQL------LEQTTGNILVVAHATTLDTCSRQLTGGVPRST------ 700
            :..|       |..||:.:::      :|.|:.:||::||.:||    |.|.|.:...|
Yeast   420 KDPYHFRFPRAESYHDLAVRMEPLLLEMEHTSKDILIIAHESTL----RVLYGYLMACTCVELPN 480

  Fly   701 -NELRQVIHKI---PYCSLATVEQVDGVWKLVEPECLPVT 736
             |..|..:.:|   |:|:  |||.::          :|:|
Yeast   481 LNFTRDKLVEISFSPFCN--TVELLN----------IPLT 508

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG13604	NP_001262894.1	UBA_UBS3B	23..60	CDD:270486
		SH3_UBASH3	275..333	CDD:212725
		His_Phos_1	494..728	CDD:278716	62/301 (21%)
YLR345W	NP_013449.1	6PF2K	71..291	CDD:396253	33/165 (20%)
YLR345W	NP_013449.1	PhoE	290..505	CDD:223483	53/260 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0406
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900