DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG13604 and Pfkfb4

DIOPT Version :9

Sequence 1:	NP_001262894.1	Gene:	CG13604 / 42840	FlyBaseID:	FBgn0039137	Length:	763	Species:	Drosophila melanogaster
Sequence 2:	XP_038937937.1	Gene:	Pfkfb4 / 54283	RGDID:	3310	Length:	506	Species:	Rattus norvegicus

Alignment Length:	382	Identity:	79/382 - (20%)
Similarity:	125/382 - (32%)	Gaps:	147/382 - (38%)

- Green bases have known domain annotations that are detailed below.

  Fly   383 PDIIEGSSFEESEQSVEKYLRQTLKPCLELPSVQLLNSH-NLTHQHNPNTPTIEITTNMSSSSTS 446
            ||.:.    .:|:::.|.::|:.  .|.|       ||: :|..:.:...|..|:        .:
  Rat   177 PDYVN----RDSDEATEDFMRRI--ECYE-------NSYESLDEEQDRWIPWAEL--------RA 220

  Fly   447 MSKQPVDEILVEPPAAQPP-RPDDTLSVHSDHSL-----------------HPGS-----LDASH 488
            :...||...::  |.|.|| :...|.|:..|.|.                 |..|     |...|
  Rat   221 LQLVPVAAAVL--PRAWPPSQALSTFSLARDLSYIKIMDVGQSYVVNRVADHIQSRIVYYLMNIH 283

  Fly   489 AKNRKIYIMRHGERVDFTFGTWIPYCFDEFGNYMRKDLNMPKTLPRRKNSPEGWQNDSPLTNVGV 553
            ...|.||:.||||                      .:||:...:          ..|..|:..|.
  Rat   284 VTPRSIYLCRHGE----------------------SELNLKGRI----------GGDPGLSPRGR 316

  Fly   554 YQANLIGQALLEAQVQIDHVYCSPSYRCIQTCTSALEGLKLTGKQKIKLEPGLFEWMAWYPSGVP 618
            ..:..:.|.:.:..::...|:.|...|.|||.    |.|.:..:|
  Rat   317 EFSKHLAQFISDQNIKDLKVWTSQMKRTIQTA----EALSVPYEQ-------------------- 357

  Fly   619 DWLTKNELTEAKFDVDLDYEPVQPASELTARLK------------ESTEQFYERNHDVILQLLEQ 671
             |...||: :|....::.||.:|....|...|:            ||.|...:|...||::|..|
  Rat   358 -WKVLNEI-DAGVCEEMTYEEIQDHYPLEFALRDQDKYRYRYPKGESYEDLVQRLEPVIMELERQ 420

  Fly   672 TTGNILVVAH--------ATTLDTCSRQLTGGVPRSTNELRQVIHKIPY--CSLATV 718
            .  |:||:.|        |..||..:.:|                  ||  |.|.||
  Rat   421 E--NVLVICHQAVMRCLLAYFLDKAAEEL------------------PYLKCPLHTV 457

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG13604	NP_001262894.1	UBA_UBS3B	23..60	CDD:270486
		SH3_UBASH3	275..333	CDD:212725
		His_Phos_1	494..728	CDD:278716	52/247 (21%)
Pfkfb4	XP_038937937.1	6PF2K	30..286	CDD:396253	26/131 (20%)
Pfkfb4	XP_038937937.1	His_Phos_1	289..475	CDD:395236	52/247 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0406
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900